The use of preserved equine renal capsule to repair lamellar corneal lesions in normal dogs

Andrade, Alexandre Lima de; Laus, José Luiz; Figueiredo, Florêncio; Batista, Cristina Mendes

doi:10.1046/j.1463-5224.1999.00052.x

Cited by 47 publications

(63 citation statements)

References 7 publications

(9 reference statements)

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“…Our results showed that photophobia/blepharospasm/epiphora were significant in the early period after surgery (3) , and may be due to the scleral edema stimulating the scleral nerves and the sutures stimulating the conjunctival eyelid. Sutures were not removed to avoid additional maneuvres that could possibly interfere in the surgical site.…”

Section: Discussionmentioning

confidence: 66%

“…Many methods have been described for repair of deep corneal ulcers and perforations, and yet, with the exception of penetrating keratoplasties with autogenous grafts, corneal opacification may be the final result (3) . In humans, biological prosthesis can be performed by reconstructing the anterior ocular segment (5,15) .…”

Section: Discussionmentioning

confidence: 99%

“…The equine renal capsule was preserved in 98% glycerine (3)(4)14) . The biological prosthesis was harvested from horses that were euthanized due to orthopedic fractures but otherwise healthy.…”

Section: Biological Prosthesismentioning

confidence: 99%

“…The ocular signs evaluated were blepharospasm/photophobia, ocular discharge, conjunctival edema and hyperemia (3) . These evaluations were performed by two observers.…”

Section: Clinical and Morphological Evaluationmentioning

confidence: 99%

“…Preserved biological membranes have been used in human and veterinary ophthalmology with good results for corneal and scleral tectonic repair (3)(4)(5)(6) . Surgical techniques employed for scleromalacia include homologous grafts of sclera (7)(8) , fascia lata graft (9)(10)(11)(12) ; aorta graft (13) and preserved heterologos pericardium (14) .…”

Section: Introductionmentioning

confidence: 99%

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Repair of lamellar scleral lesions in dogs with preserved equine renal capsule: short report

Andrade¹,

Eugênio²,

Vasconcelos³

et al. 2004

Arq. Bras. Oftalmol.

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Repair of lamellar scleral lesions in dogs with preserved equine renal capsule -Short reportPurpose: To evaluate the use of equine renal capsule preserved in glycerin to repair lamellar scleral lesions in dogs. Methods: Twelve healthy mongrel dogs, male and female, weighing 12 kg were used. The study was both clinical and morphological, and performed on the first, third, seventh, 15 th , 30 th and 60 th day after surgery. Temporal canthotomy was performed after standard preoperative and general anesthesia. Conjunctival and scleral square incisions of 0.5x0.5 cm were carried out in a one o'clock position, near the limbus. A fragment of hydrated biological prosthesis, of the same shape, was sutured with 7-0 Vicryl ® in an interrupted suture. Results: The clinical evaluation showed blepharospasm/photophobia until the 7 th day after surgery. Conjunctival edema appeared up to the 5 th day after surgery. Mucoid ocular discharge was sustained until the 10 th day after surgery. Hyperemia was observed until the end of the evaluation period. There were no signs of graft extrusion in all animals. The anterior and posterior segments did not show clinical signs of inflammation. The optical microscopy morphological evaluation showed an inflammatory exudation with acute aspects in the early and intermediate periods, and inflammatory exudation with chronic aspects in the late periods. There was incorporation of the implant by the recipient's sclera. Conclusion: These results suggest that the equine renal preserved capsule could be a useful alternative tissue to repair lamellar corneal lesions in dogs and humans.ABSTRACT

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Section: Discussionmentioning

confidence: 66%

Section: Discussionmentioning

confidence: 99%

Section: Biological Prosthesismentioning

confidence: 99%

“…The ocular signs evaluated were blepharospasm/photophobia, ocular discharge, conjunctival edema and hyperemia (3) . These evaluations were performed by two observers.…”

Section: Clinical and Morphological Evaluationmentioning

confidence: 99%