1995
DOI: 10.1136/jnnp.58.2.250
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The use of PET in evaluating patients with primary brain tumours: is it useful?

Abstract: Thus PET seems to be of limited value as an aid to evaluating and treating patients with suspected or known primary brain tumours. (7 Neurol Neurosurg Psychiatry 1995;58:250-252)

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Cited by 85 publications
(41 citation statements)
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“…29,31,33 PET imaging has better spatial resolution (0.1-0.2 cm 3 ) than MR spectroscopy. 33,34 [ 18 F]fluorodeoxyglucose has been the most widely studied agent, and initial reports suggested an ability to differentiate PTRE from tumor recurrence 35,36 ; subsequent studies, however, suggest the accuracy is significantly lower than that in initial reports. [37][38][39] Other PET tracers such as 13 …”
Section: Discussionmentioning
confidence: 99%
“…29,31,33 PET imaging has better spatial resolution (0.1-0.2 cm 3 ) than MR spectroscopy. 33,34 [ 18 F]fluorodeoxyglucose has been the most widely studied agent, and initial reports suggested an ability to differentiate PTRE from tumor recurrence 35,36 ; subsequent studies, however, suggest the accuracy is significantly lower than that in initial reports. [37][38][39] Other PET tracers such as 13 …”
Section: Discussionmentioning
confidence: 99%
“…Bioluminescence imaging revealed antitumor activity compared with CPT-11 in combination with bevacizumab. However, antiangiogenic agents can suppress the extravasation of contrast agents such as gadolinium, and gadolinium-contrast magnetic resonance imaging may give a false response (28). This means that bevacizumab is suspected of having a negative effect on bioluminescence imaging by reducing the permeability of tumor vessels.…”
Section: Discussionmentioning
confidence: 99%
“…However, recent studies have demonstrated some diagnostic limitations of 18 F-FDG PET (39,40). Because of the high rate of physiologic glucose metabolism in normal brain tissue, the detectability of tumors with only modest increases in glucose metabolism, such as low-grade tumors and in some cases recurrent high-grade tumors, is difficult.…”
Section: F-fdg Petmentioning
confidence: 99%