The use of MMSE and MoCA in patients with acute ischemic stroke in clinical

Shen, Yijun; Wang, Wen-An; Huang, Fu-De; Chen, Jie; Liu, Haiyan; Xia, Yiling; Han, Meng; Zhang, Le

doi:10.3109/00207454.2015.1031749

Cited by 37 publications

(24 citation statements)

References 27 publications

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“…56 It has also been able to identify subtle but clinically relevant cognitive deficits with greater frequency than MMSE, especially in populations with MCI and chronic heart failure 57 and acute ischemic stroke. 58 The MoCA is designed to be more sensitive to minor cognitive deficits than the MMSE and thus may be a superior screening instrument for MCI and vascular AD, as well as chronic heart failure, stroke, and Parkinson disease. 59 In addition, the MoCA consists of subscales, including memory, executive function, attention, orientation, language, and visuospatial function, which increases the sensitivity of this instrument over the MMSE.…”

Section: Resultsmentioning

confidence: 99%

The Utility of Cognitive Screeners in the Detection of Dementia Spectrum Disorders in Spanish-Speaking Populations

Burke

Grudzien

Burgess

et al. 2020

J Geriatr Psychiatry Neurol

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Increasing rates of dementia spectrum disorders among Spanish-speaking geriatric populations necessitate the development of culturally appropriate cognitive screening tests that can identify neurodegenerative disorders in their earliest stages when emerging disease-modifying treatments are most likely to be effective. This scoping review identified 26 brief Spanish language cognitive screening tools (<20 minutes) by searching academic databases using a combination of search terms. Results suggest that the Mini-Mental Status Examination and Montreal Cognitive Assessment appear to be less valid than other screeners. Instruments such as the 7-Minute Screen and Mini-Cog evidence higher classification rates of dementia, while Phototest detected mild cognitive impairment at higher rates more consistently than other screeners. Different sensitivity and specificity outcomes and cutoffs were observed when the same cognitive screener was evaluated in different countries. Results indicate that it is imperative to increase nation-specific validation and normative data for these instruments to best serve diverse populations.

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Section: Resultsmentioning

confidence: 99%

The Utility of Cognitive Screeners in the Detection of Dementia Spectrum Disorders in Spanish-Speaking Populations

Burke

Grudzien

Burgess

et al. 2020

J Geriatr Psychiatry Neurol

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“…Differences between contrasting groups with various degrees of severity of vascular cognitive impairment were highlighted in many studies 1419 , 24 , 31 , 41 , 45 , 46 , 49 , 58 , 60 , 62 , 66 However, studies need to improve the control of variables such as sociodemographic (age and education) and neurological data (cerebrovascular disease) that influence patient cognitive performance 446…”

Section: Discussionmentioning

confidence: 99%

“…Some studies support the high sensitivity of the MoCA18 , 46 , 51 , 54, but reveal its low specificity 1214 , 24 , 42 , 48 , 49 , 52 , 57 , 62 Chan et al12 found that 77% of patients were classified as cognitively intact on the MoCA but were impaired for one or more cognitive domains on a neuropsychological assessment (intellectual functioning, processing speed, and visual memory) not evaluated by the screen.…”

Section: Discussionmentioning

confidence: 99%

“…The MMSE is more specific than the MoCA,24 , 46 but is less sensitive for stroke patients 643 , 45 This instrument can show differences between clinical and control groups16 , 17 , 41 and between various cerebrovascular diseases,16 , 24 , 46 but underestimates cognitive impairment post-stroke 40. However, the MMSE has shown low prediction ability for functional outcomes 44…”

Section: Discussionmentioning

confidence: 99%

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Psychometric properties of cognitive screening for patients with cerebrovascular diseases A systematic review

Rodrigues

Becker

Beckenkamp

et al. 2019

Dement. neuropsychol.

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ABSTRACT. Screening instruments are ideal for acute clinical settings because they are easy to apply, fast, inexpensive and sensitive for specific samples. However, there is a need to verify the psychometric properties of screening in stroke patients. Objective: This study investigated the psychometric properties (methodological procedures) of cognitive screening for patients with cerebrovascular diseases. Methods: A systematic review of papers published on PsycINFO, Web of Knowledge, PubMed and Science Direct (2005 to 2016) was performed. Results: A total of 55 articles remained after applying exclusion criteria. The samples ranged from 20 to 657 patients. Most articles evaluated elderly individuals with four to 13 years of education who had experienced ischemic or hemorrhagic stroke. There was a tendency to find evidence of validity for criteria and to analyze the sensitivity/specificity of the instruments. Although the studies frequently used the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) to seek evidence of validity and reliability, the use of these instruments among stroke patients has been criticized due to their psychometric properties and the neuropsychological functions evaluated. Conclusion: Although there is no gold standard screen for assessing adults post-stroke, instruments devised specifically for this population have shown promise. This review helps both researchers and clinicians to select the most appropriate screen for identifying cognitive impairment in adults post-stroke.

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“…These results could be attributed to that the sensitivity of MMSE is slightly lower than MoCA as screening test for detection the cognitive impairment particularly processing speed and executive function. MMSE is less capable of testing for complex cognitive impairments in domains such as visuospatial, executive function, and abstract reasoning that are commonly affected in stroke patients [26].…”

Section: Discussionmentioning

confidence: 99%

Post-stroke executive dysfunction and verbal fluency negatively correlated to IL8

Shaheen

Daker

Abbass

et al. 2019

Egypt J Neurol Psychiatry Neurosurg

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Background: Patients with acute ischemic stroke are at a higher risk of developing cognitive impairment which could be often attributed to cytokine activation. Objectives: To explore the relationship between the cognitive performance and the inflammatory markers in the ischemic stroke patients at the early stage. Patients and methods: A cross-sectional case-control study was performed on 44 ischemic stroke patients. The patients underwent the following battery of evaluation: (A) assessment of stroke disability by modified Rankin Scale (mRS) and National Institute of Health Stroke Scale (NIHSS). (B) neuropsychological evaluation using Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA) scale, trail making test (TMT), and Controlled Oral Word Association Test (COWAT). (C) Assessment of depression was done by using Beck Depression Inventory (BDI). Measurement of the serum levels of ESR, C-reactive protein, and IL-8 was done. This study included 44 ages, sex, and educational level matched controls for comparison of neuropsychological tests and serum level of IL-8. Results: The patients showed worse performance in neuropsychological tests (MMSE, MoCA, COWAT, TMT) than the controls. There was a significant negative correlation between the serum level of IL-8 and (MoCA) (r = − 0.43, p = 0.004), verbal fluency (r = − 0.56, p < 0.001), and positive significant correlation between IL8 and executive functions (r = 0.61, p < 0.001). Conclusion: The cognitive impairment in early acute ischemic stroke is highly correlated to the serum level of IL-8.

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The use of MMSE and MoCA in patients with acute ischemic stroke in clinical

Abstract: Neuropsychological performance of stroke patients was influenced by biological and demographic variables: age, diabetes and intracranial atherosclerosis. The MoCA and MMSE are both reliable assessments for the diagnosis of cognitive impairment after stroke.

Cited by 37 publications

References 27 publications

The Utility of Cognitive Screeners in the Detection of Dementia Spectrum Disorders in Spanish-Speaking Populations

The Utility of Cognitive Screeners in the Detection of Dementia Spectrum Disorders in Spanish-Speaking Populations

Psychometric properties of cognitive screening for patients with cerebrovascular diseases A systematic review

Post-stroke executive dysfunction and verbal fluency negatively correlated to IL8

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