“…It is found only in cultivation, where it is the most commonly grown of all plants in the nicotiana genus and its leaves are commercially grown in many countries to be processed into tobacco 1,2 . In addition to being used in cigarette industry, N. tabacum is also used as insecticide, anesthetic, diaphoretic, sedative and emetic agents in Chinese folklore medicine because of it containing many useful chemical compounds 1,[3][4][5] . In previous work, a number of bioactive compounds, such as terpenoids [6][7][8] , alkaloids 9,10 , lignans 11,12 , flavonoid 13 , phenyl-propanoids 14 and the homologous, were isolated from this plant.…”