The Use of Intraoperative Small and Large Field of View Gamma Cameras for Radioguided Surgery

Hellingman, Daan; Vidal-Sicart, Sergi

doi:10.1007/978-3-319-26051-8_3

Cited by 5 publications

(7 citation statements)

References 83 publications

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“…To our knowledge, intraoperative usage with PET radiopharmaceuticals has not been shown in literature yet. Specific reviews reporting on portable γ cameras in more detail are provided by Tsuchimochi et al and Hellingman et al [150,151].…”

Section: Portable Gamma (γ) Camerasmentioning

confidence: 99%

“…Effectively, camera exposure times used during surgery range between 5 and 60 s [106]. Typical system resolutions of a portable γ camera, at distances <5 cm to the targeted tissue, are found between roughly 1.5-10 mm [150,151]. Typical collimator designs are the parallel-hole and the pinhole collimators, fabricated out of lead or tungsten [153].…”

Section: Portable Gamma (γ) Camerasmentioning

confidence: 99%

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Recent advances in nuclear and hybrid detection modalities for image-guided surgery

Oosterom

Rietbergen

Welling

et al. 2019

Expert Review of Medical Devices

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Introduction: Radioguided surgery is an ever-evolving part of nuclear medicine. In fact, this nuclear medicine sub-discipline actively bridges non-invasive molecular imaging with surgical care. Next to relying on the availability of radio-and bimodal-tracers, the success of radioguided surgery is for a large part dependent on the imaging modalities and imaging concepts available for the surgical setting. With this review, we have aimed to provide a comprehensive update of the most recent advances in the field. Areas covered: We have made an attempt to cover all aspects of radioguided surgery: 1) the use of radioisotopes that emit γ, β + , and/or β − radiation, 2) hardware developments ranging from probes to 2D cameras and even the use of advanced 3D interventional imaging solutions, and 3) multiplexing solutions such as dual-isotope detection or combined radionuclear and optical detection. Expert opinion: Technical refinements in the field of radioguided surgery should continue to focus on supporting its implementation in the increasingly complex minimally invasive surgical setting, e.g. by accommodating robot-assisted laparoscopic surgery. In addition, hybrid concepts that integrate the use of radioisotopes with other image-guided surgery modalities such as fluorescence or ultrasound are likely to expand in the future.

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Section: Portable Gamma (γ) Camerasmentioning

confidence: 99%

Section: Portable Gamma (γ) Camerasmentioning

confidence: 99%

Recent advances in nuclear and hybrid detection modalities for image-guided surgery

Oosterom

Rietbergen

Welling

et al. 2019

Expert Review of Medical Devices

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“…However, experts feel that despite the various technical improvements, a gamma probe will still be a part of the intraoperative technical equipment for SLNB and will not be completely replaced by portable gamma cameras or fhSPECT/gamma camera systems [14].…”

Section: Toward Intraoperative 3d Imagingmentioning

confidence: 99%

“…Sentinel lymph node biopsy in the pelvic and HN area is, however, challenging and reserved for experienced centers owing to the complex anatomy of these regions and the limitations of standard technical equipment [14][15][16][17][18][19]: (a) The lymphatic system in these anatomic areas is complex and includes hundreds of LNs adjacent to vulnerable structures such as nerves or vessels. (b) Lymphatic drainage of HN or urogenital cancers may be unpredictable, and cancers may drain to aberrant and multiple nodal basins.…”

Section: Introductionmentioning

confidence: 99%

New technologies in radioguided surgery in complex anatomic areas

Bluemel

Herrmann

2016

Clin Transl Imaging

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Sentinel lymph node biopsy (SLNB) is the most common radioguided surgery procedure and standard of care for lymph node staging in clinically node-negative patients with melanoma and breast cancer. While SLNB has also emerged as a potential alternative to lymph node dissection for staging in patients with other solid malignancies, its use for this purpose has to date not been widely accepted owing to technical limitations in complex anatomic areas such as the head and neck and the pelvic region. However, new technologies have recently been developed to overcome these limitations. This review focuses on the new technologies that improve SLN localization in complex anatomic areas, including new diagnostic tracers ( 99m Tc-tilmanocept and hybrid tracers), preoperative SPECT/CT imaging, and scintigraphic threedimensional intraoperative imaging techniques.

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“…The success of RGS depends on the progress of the research on radiopharmaceuticals and intraoperative probes. Both counting probes and imaging probes (in the form of small field-of-view compact gamma cameras) have been devised [15,16]. Imaging probes provide, in real time, a map of the radiopharmaceutical activity distribution in the anatomical region of interest (ROI).…”

Section: Introductionmentioning

confidence: 99%