The use of intraoperative neuroimaging tools and a navigation system in surgical treatment of primary and metastatic tumors of the spine

Konovalov, Nikolay; Nazarenko, A G; Asyutin, D S; Onoprienko, R A; Korolishin, V A; Cherkiev, I U; Martynova, M A; Закиров, Б А; Тimonin, S Yu; Kosyrkova, Alexandra

doi:10.17116/neiro20168025-14

Cited by 10 publications

(6 citation statements)

References 12 publications

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“…X-ray plain film can be available to find most of the vertebral tumors. Its diagnostic principle is that it has relatively high sensitivity and relatively high spatial resolution in imaging bone tissues, and can clearly show the size and the structure of the bone as well as the destruction on the bones in the skeleton and the periosteal reaction based on the change in bone mineral density caused by the change in the concentration of calcium in the spine (4,9). However, it cannot be used for the examination and analysis of cartilage lesions due to its limitations, and the adnexal tumors and those under the adnexa are easy to be omitted.…”

Section: Discussionmentioning

confidence: 99%

“…A total of 69 patients with primary spinal osseous tumors who received treatment in Nankai Hospital (Tianjin, China) from July 2016 to June 2017 were selected into the study. It was confirmed by pathological diagnosis that all the patients suffered from the disease, and all of them received X-ray, computed tomography (CT) and magnetic resonance imaging (MRI) examinations (4). General data of study patients are given in Table I.…”

Section: Methodsmentioning

confidence: 96%

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Imaging features of primary spinal osseous tumors and their value in clinical diagnosis

Yang

Zhang

et al. 2018

Oncol Lett

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This study explored the method of imaging diagnosis of primary spinal osseous tumors and the application value of imaging in clinical diagnosis. Sixty-nine patients with primary spinal osseous tumors who received treatment in Nankai Hospital from July 2016 to June 2017 were selected. All of them received X-ray, computed tomography (CT) and magnetic resonance imaging (MRI) examinations to analyze the imaging features of the three examination methods. Sensitivity (Sen), specificity (Spe), positive predictive value (PV+), negative predictive value (PV−) and accuracy (Acc) were compared. The consistency of the three examination methods in diagnosing primary spinal osseous tumors was analyzed. Sen, Acc and PV− of the three examination methods in diagnosing spinal osseous tumors had obvious differences. MRI showed the highest Sen (P<0.05). MRI had relatively high consistency with CT scan in diagnosing primary spinal osseous tumors, and κ-value was 0.72. CT scan and X-ray had obvious difference in diagnosing primary spinal osseous tumors (P<0.05). The consistency between CT scan and X-ray in diagnosing primary spinal osseous tumors was relatively low, and κ-value was 0.47. MRI and X-ray had obvious difference in diagnosing primary spinal osseous tumors (P<0.05). The consistency between MRI and X-ray in diagnosing primary spinal osseous tumors was relatively low, and κ-value was 0.41. X-ray examination is easy to operate with high resolution. CT scan has obvious advantages in displaying lesions with complex structure, many of which locate in overlapping sites. MRI has more advantages and higher accuracy in judging the scope of the tumor. CT and MRI examinations have obviously higher efficacy than X-ray in diagnosing primary spinal osseous tumors. They are conducive in improving the accuracy of diagnosing primary spinal osseous tumors.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 96%

Imaging features of primary spinal osseous tumors and their value in clinical diagnosis

Yang

Zhang

et al. 2018

Oncol Lett

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“…-рентгенография является малоинформативным методом диагностики мтС позвоночника, но он позволяет выявить кифотическую или сколиотическую деформацию в положении стоя в отличии от мрт или Кт, которые выполнены лежа [15,21].…”

Section: методы диагностикиunclassified

Metastatic Lesion of the Spine: Diagnosis and Tactics of Surgical Treatment

Yarikov¹,

Yermolaev²,

Smirnov³

et al. 2019

Problems in oncology

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Epidemiological studies show an increase in the number of people with cancer. Bone metastases are a frequent manifestation of generalized cancer, because it is in malignant tumors of the spine more often than other bones of the skeleton becomes a target for metastasis. The article describes in detail the methods of diagnosis of spinal lesions in cancer pathology. Particular attention is paid to the scales reflecting the severity of the patient’s condition, the degree of spinal cord damage, the severity of pain in metastasis to the spine, the prognosis of survival in oncovertebrology and evaluation of the stability of the spine in metastatic lesions. Further, the paper presents non-radical (decompression, vertebroplasty) and radical (spondylectomy, corporectomy) surgical methods of treatment

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“…However, during the course of surgical treatment of spinal tumors, the risk of intraoperative complications is very high, including damage to the spinal cord and its roots, and great vessels both in the process of tumor resection and implantation of corporal or pedicle screws. Hence, the regimens of metastatic spine tumors remain to be determined …”

Section: Introductionmentioning

confidence: 99%

“…Hence, the regimens of metastatic spine tumors remain to be determined. 5,6 Re-Recently, many assays have demonstrated that the hedgehog (Hh) signaling pathway may be a novel targeted regimen in cancers. [7][8][9] Therefore, the targeted treatments of the Hh signaling pathway, which are designed to interfere with the way in which tumors grow and survive, provide new hope for the treatment of metastatic spine tumors.…”

Section: Introductionmentioning

confidence: 99%

Epigenetic silencing of sonic hedgehog elicits antitumor immune response and suppresses tumor growth by inhibiting the hedgehog signaling pathway in metastatic spine tumors in Sprague‐Dawley rats

Shi

Zhang²,

et al. 2018

J of Cellular Biochemistry

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The use of intraoperative neuroimaging tools and a navigation system in surgical treatment of primary and metastatic tumors of the spine

Cited by 10 publications

References 12 publications

Imaging features of primary spinal osseous tumors and their value in clinical diagnosis

Imaging features of primary spinal osseous tumors and their value in clinical diagnosis

Metastatic Lesion of the Spine: Diagnosis and Tactics of Surgical Treatment

Epigenetic silencing of sonic hedgehog elicits antitumor immune response and suppresses tumor growth by inhibiting the hedgehog signaling pathway in metastatic spine tumors in Sprague‐Dawley rats

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