The use of interferon in medicine

Abstract

Interferons are low-molecular weight glycoproteins. They are characterized by paracrine and autocrine activity. Their production and release occurs through various types of cells, which ultimately leads to the protection of the body against viral infections. Interferons do not have direct antiviral activity but affect cells, inducing the formation of antiviral agents and "antiviral readiness" in them. Thanks to their properties interferons have been widely used in the treatment of many diseases, among others hepatitis B, hepatitis C and multiple sclerosis. In addition, they show anti-cancer effects, even in the case of chronic myeloid leukemia. They are currently an important element in the search for a drug against SARS-CoV-2.

Antiviral Chemotherapy in Avian Medicine—A Review

“…Divided into three classes, type I, type II, and type III, IFNs do not have direct antiviral activity but affect cells, inducing the synthesis of antiviral agents. Interferons activate a number of enzymes in the cell that allow the degradation of viral genetic material, causing the so-called antiviral status [ 112 ]. In human medicine, IFNs have been widely used in the treatment of many diseases, such as hepatitis B, hepatitis C, and multiple sclerosis [ 112 ].…”

“…Interferons activate a number of enzymes in the cell that allow the degradation of viral genetic material, causing the so-called antiviral status [ 112 ]. In human medicine, IFNs have been widely used in the treatment of many diseases, such as hepatitis B, hepatitis C, and multiple sclerosis [ 112 ]. IFNs also show anti-cancer effects.…”