The use of immunohistochemistry in the differential diagnosis of primary cutaneous adnexal neoplasms and metastatic adenocarcinomas to the skin

Prieto, Víctor G.; Ivan, Doina

doi:10.1016/j.mpdhp.2010.08.001

Cited by 2 publications

(1 citation statement)

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“…A definite primary could not be established in these cases as they were lost to follow‐up. Immunocytochemistry is known to be helpful in such cases in identifying the primary tumor; however, it was not available to us at that time . Didolkar et al and Osteen et al have reported that in many cases of cutaneous metastasis, in spite of thorough clinical investigation and even an autopsy, a primary may not be found.…”

Section: Discussionmentioning

confidence: 99%

Role of FNAC in palpable chest wall lesions in developing country

Goyal

Sharma

Bahl

2014

Diagnostic Cytopathology

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Palpable chest wall lesions are unusual manifestation of an underlying thoracic pathology and it is difficult to diagnose them with their diverse spectrum ranging from benign to malignant. Considering the exposure of patient to invasive biopsy/excision and the risk of local complications, FNAC is now being increasingly used in the primary assessment of these lesions. Objectives of this study were to report the spectrum of chest wall lesions in the population of a developing country and evaluating the diagnostic role of FNAC. All the patients who presented with palpable cutaneous or subcutaneous chest wall swelling during a period of January 2003 to August 2010 were reviewed retrospectively. May Grunwald Giemsa and Papanicolaou stained aspirates were examined, along with special stains. Seven hundred seventy-three cases were subjected to chest wall FNAC, of which 726 (93.9%) cases were satisfactory. Age ranged from 1 to 93 years with M:F = 0.92:1. 358 (49.3%) were diagnosed as inflammatory and 368 (50.7%) were neoplastic lesions. Two-hundred thirty four cases (32.2%) were diagnosed as mycobacterial abscess (likely tuberculous). Of the neoplastic lesions, 153 were malignant with carcinomas being predominant (88.2%). Malignant cases comprised of scar site recurrence in breast carcinoma (73 cases), metastatic carcinomas (62 cases), primary sarcomas (eight cases), hematological neoplasms (six cases), and miscellaneous group (four cases). Overall malignant lesions accounted for 21.1% (153/726) of satisfactory chest wall aspirates. FNAC is very useful and simple investigation for early diagnosis of chest wall abscesses, cutaneous metastases from visceral malignancies, and scar site recurrence in breast carcinoma.

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Section: Discussionmentioning

confidence: 99%