Abstract:The present study evaluated ethno medicinal knowledge of people in the rural community of São Sebastião, Vitória da Conquista, Bahia, Brazil. Using semi-structured interviews, 84 randomly chosen individuals informed about the use of traditional medicinal plants in their community, thereby identifying their therapeutic potential, which were categorized according to the ICD-10 (International Statistical Classification of Diseases and Related Health Problems). The collected data were analyzed with using the Infor… Show more
“…This is particularly important in most tropical countries where their rich plant biodiversity affords them the luxury to select from the plethora of plant resources with therapeutic potential. In developing countries, the use of plant medicine is the primary medical remedy for many people especially, among the rural population for treating and managing various disease conditions [ 1 ]. About 80 % of the world's population depends on herbal medicine because it is less costly, readily and easily accessible to consumers [ 2 ].…”
“…This is particularly important in most tropical countries where their rich plant biodiversity affords them the luxury to select from the plethora of plant resources with therapeutic potential. In developing countries, the use of plant medicine is the primary medical remedy for many people especially, among the rural population for treating and managing various disease conditions [ 1 ]. About 80 % of the world's population depends on herbal medicine because it is less costly, readily and easily accessible to consumers [ 2 ].…”
“…In regards to the endemic and exotic herbs used in Brazilian folk medicine and complementary therapeutical practices, several species of "arnica" are noteworthy (Athayde et al, 2019;de Athayde et al, 2021;Marisco et al, 2017;Ribeiro et al, 2017), which are typically used as remedies in the form of tisanes; tinctures; bottled; globules; hot compresses; ointments; and gels. This range of formulations is accompanied by the therapeutical versatility of arnica, which is reported to treat: postoperative lesions such as bruises, sprains and abrasions; edema related to fracture and rheumatic pain of muscles and joints; inflammatory processes of the oropharynx; furunculosis; insect bites and stings; superficial phlebitis, etc (Athayde et al, 2019;Carvalho et al, 2018;Rodríguez-Chávez et al, 2017;Saraiva et al, 2015;Siqueira et al, 2018;Souza et al, 2017).…”
Os extratos de “Arnica” são amplamente usados na medicina popular para tratar doenças inflamatórias agudas e crônicas. No entanto, seus efeitos tóxicos mediante uso sistêmico ainda não são totalmente compreendidos. Portanto, este trabalho fornece uma revisão sistemática sobre a segurança de extratos de arnica em ensaios pré-clínicos cobrindo sua administração oral e intraperitoneal em modelos animais. Para tanto, a diretriz PRISMA foi seguida e o protocolo do estudo foi registrado no PROSPERO (CDR42020167112). As pesquisas foram realizadas nas bases de dados PubMed (MEDLINE), Scopus, Science Direct, Web of Science (Science Citation Index) e Biblioteca Virtual da Saúde (BVS); enquanto a ferramenta de risco de viés do SYRCLE e o checklist CAMARADES foram usadas para avaliar a qualidade científica. De 382 artigos, cinco estudos atenderam aos critérios de elegibilidade e foram submetidos à análise qualitativa. Dados de toxicidade aguda foram relatados em todos os artigos selecionados, e o tempo de tratamento foi de até 14 dias. Além disso, as seguintes espécies foram relatadas: Solidago chilensis (categorias de perigo de 4 e 5 para administração i.p e v.o, respectivamente); Solidago microglossa (categoria de perigo de 3, i.p); Lychnophora trichocarpha (categoria de perigo ≥ 4, i.p); e Lychnophora pinaster (categoria de perigo ≥ 4, v.o). Os extratos alcoólicos apresentaram maior potencial tóxico, que aumentou de forma dose-dependente após 100 mg/Kg. Com relação à toxicidade órgão-específico, os artigos relataram hepatotoxicidade e nefrotoxicidade após análise histopatológica. No entanto, a segurança de S. chilensis, L. pinaster, L. trichocarpha e S. microglossa após a administração sistêmica permanece incerta devido à qualidade experimental limitada dos artigos incluídos, bem como a falta de relatos sobre toxicidade crônica, farmacocinética e estudos de mutagenicidade.
“…In Brazil, the leaves of S. purpurea have traditionally been used to treat gastritis (Borges & Moreira, 2016;Castro et al, 2011), hypertension (Silva et al, 2012;Marisco et al, 2017b) and diarrhea (Franco & Barros, 2006;Oliveira, Barros & Moita Neto, 2010;Freitas et al, 2012). Pharmacological studies have demonstrated its antimicrobial (Alencar et al, 2015;Miranda-Cruz et al, 2012;Marisco et al, 2017a;, antitumor , antioxidant and antiulcer potential (Almeida et al, 2017).…”
The Anacardiaceae family has species rich in secondary metabolites. They are widely used in popular medicine. Among them, Spondias purpurea L. stands out for containing several secondary metabolites with important biological activities. To aid in the precise identification of the species, this work aims to perform an anatomical and histochemical characterization of leaves of S. purpurea. Microscope slides containing cross-sections of the petiolule and leaflets, in addition to paradermal sections of the leaflets, were prepared and analyzed in an optical and polarized microscope. Histochemical tests were performed on fresh leaflets. Through microscopic analysis, it was possible to identify the anatomical structures that allow the diagnosis of the studied species, such as petiolule with concave-convex shape, non-glandular and glandular trichomes, druses in phloem; leafletsamphistomatic, with non-glandular trichomes on the adaxial face and glandular trichomes on the abaxial face, midrib with concave-convex shape, two collateral vascular bundles, one layer of palisade parenchyma, druses in phloem and mesophyll. Through histochemistry, the presence of phenolic compounds, alkaloids, tannins, triterpenes, steroids, lipophilic compounds, essential oils, lignin, starch and calcium oxalate crystals were evidenced in the leaflets. The results are important for the quality control of plant material.
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