The use of graduated compression stockings in the prevention of postoperative deep vein thrombosis

Allan, A.; Williams, Jeff T.; Bolton, J. P.; Quesne, L. P. Le

doi:10.1002/bjs.1800700311

Cited by 119 publications

(44 citation statements)

References 20 publications

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“…20 Increased hematocrit has been the only predictive factor of venous and arterial thrombosis in subjects with polycythemia vera, whereas high platelet counts and abnormal platelet function were not significantly linked to polycythemia vera-associated thrombosis. 9,11,12 Rheological therapies, including compression devices 21 and hemodilution with dextran, 22 have been shown to reduce the risk of deep vein thrombosis in patients with polycythemia vera.…”

Section: Discussionmentioning

confidence: 99%

Hematocrit and risk of venous thromboembolism in a general population. The Tromso study

Brækkan¹,

Mathiesen²,

Njølstad³

et al. 2009

Haematologica

163

119

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BackgroundHematocrit above the normal range for the population, such as in primary or secondary erythrocytosis, predisposes to both arterial and venous thrombosis. However, little is known about the association between hematocrit and risk of venous thromboembolism in a general population. Design and MethodsHematocrit and related hematologic variables such as hemoglobin, red blood cell count, mean corpuscular volume, and baseline characteristics were measured in 26,108 subjects, who participated in the Tromsø Study in 1994-1995. Incident venous thromboembolic events during follow-up were registered up to September 1 st , 2007. ResultsThere were 447 venous thromboembolic events during a median of 12.5 years of followup. Multivariable hazard ratios per 5% increment of hematocrit for the total population, adjusted for age, body mass index and smoking, were 1.25 (95% CI: 1.08-1.44) for total venous thromboembolism and 1.37 (95% CI: 1.10-1.71) for unprovoked venous thromboembolism. In category-based analyses, men with a hematocrit in the upper 20 th percentile (≥46% in men) had a 1.5-fold increased risk of total venous thromboembolism (95% CI: 1.08-2.21) and a 2.4-fold increased risk of unprovoked venous thromboembolism (95% CI: 1.36-4.15) compared to men whose hematocrit was in the lower 40 th percentile. The risk estimates were higher for men than for women both in continuous and category-based analyses. The findings for hemoglobin and red blood cell count were similar to those for hematocrit, whereas mean corpuscular volume was not associated with venous thromboembolism. ConclusionsOur findings suggest that hematocrit and related hematologic variables such as hemoglobin and red blood cell count are risk factors for venous thromboembolism in a general population.Key words: hematocrit, population range, arterial and venous thrombosis. Study. Haematologica. 2010; 95:270-275. doi:10.3324/haematol.2009 Hematocrit and risk of venous thromboembolism in a general population. The Tromsø study Citation: Braekkan SK, Mathiesen EB, Njølstad I, Wilsgaard T, and Hansen J-B. Hematocrit and risk of venous thromboembolism in a general population. The Tromsø

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Section: Discussionmentioning

confidence: 99%

Hematocrit and risk of venous thromboembolism in a general population. The Tromso study

Brækkan¹,

Mathiesen²,

Njølstad³

et al. 2009

Haematologica

163

119

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“…A postal survey of orthopaedic surgeons in the UK showed that 68% used graded compression stockings as prophylaxis for DVT (Laverick, Croal and Mollan 1991). Their efficacy has been well documented in abdominal surgery (Holford 1976;Scurr et al 1977;Allan et al 1983;Turner, Cole and Brooks 1984;Wille-Jorgensen et al 1985;Jeffery and Nicolaides 1990), but there is little information on their use in orthopaedic surgery (Barnes et al 1978;Ishak and Morley 1981;Ohlund, Fransson and Starck 1983).…”

Section: Graded Compression Stockings For Prevention Of Deep-vein Thrmentioning

confidence: 99%

Graded Compression Stockings for Prevention of Deep-Vein Thrombosis After Hip and Knee Replacement

Hui

Heras-Palou

Dunn

et al. 1996

The Journal of Bone and Joint Surgery. British volume

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We performed a prospective, randomised controlled trial in 177 patients who were having either total hip or knee replacement, to evaluate the use of both above-and below-knee graded compression stockings in the prevention of deep-vein thrombosis (DVT).With above-knee stockings, we found no significant reduction of the overall, proximal or major calf (> 5 cm) DVT rates. With below-knee stockings, the overall thrombosis rate was similar to that of the control group but the stockings appeared to have altered the pattern of thrombosis. Patients who had total hip replacement and wore below-knee stockings had a significantly higher rate of proximal or major calf DVT (p = 0.03). This pattern was reversed in patients with total knee replacement who developed a significantly lower rate of proximal or major calf DVT with below-knee stockings (p < 0.05).Our results showed that, with the exception of below-knee stockings in knee replacement patients, graded compression stockings were ineffective in preventing DVT after hip or knee replacement surgery.

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“…This modal ity has been demonstrated to be effective in low risk surgery. 21 The combination of the References Prophylaxis of deep vein thrombosis 561 above modalities is designed to reduce stasis, one of the major arms of Virchow's Triad. Low dose heparin (5,000 U, SC, 012 hrs) was chosen for its effect on redu cing hypercoagulability, another arm of Virchow's Triad.…”

Section: Discussionmentioning

confidence: 99%

Mechanical plus pharmacological prophylaxis for deep vein thrombosis in acute spinal cord injury

Crabbe

Doyle

et al. 1992

Spinal Cord

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The use of graduated compression stockings in the prevention of postoperative deep vein thrombosis

Cited by 119 publications

References 20 publications

Hematocrit and risk of venous thromboembolism in a general population. The Tromso study

Hematocrit and risk of venous thromboembolism in a general population. The Tromso study

Graded Compression Stockings for Prevention of Deep-Vein Thrombosis After Hip and Knee Replacement

Mechanical plus pharmacological prophylaxis for deep vein thrombosis in acute spinal cord injury

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