The use of foam sclerotherapy for the treatment of head and neck vascular malformations

Rehman, Khaleeq-Ur; Sittampalam, G.; McCafferty, Ian; Monaghan, Andrew

doi:10.1016/j.bjoms.2009.03.007

Cited by 8 publications

(2 citation statements)

References 3 publications

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“…STS has been used to treat cutaneous vascular malformations throughout the body, esophageal varices, spermatoceles, hydroceles, and epididymal cysts. In the head and neck lymphovascular malformations,51,52 facial telangiectasia,53 and craniofacial venous malformations54 have been treated with STS and similar agents. Foam sclerotherapy is a popular variation of the method.…”

Section: Discussionmentioning

confidence: 99%

Office‐based sclerotherapy for recurrent epistaxis due to hereditary hemorrhagic telangiectasia: a pilot study

Boyer

Fernandes

Durán

et al. 2011

Int Forum Allergy Rhinol

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Section: Discussionmentioning

confidence: 99%

Office‐based sclerotherapy for recurrent epistaxis due to hereditary hemorrhagic telangiectasia: a pilot study

Boyer

Fernandes

Durán

et al. 2011

Int Forum Allergy Rhinol

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“…One alternative is sclerotherapy, by injecting vascular lesions with an agent that causes thickening of the vessel wall, obstruction of blood flow, clot formation, and collapse of the lesion. An established treatment modality for vascular malformations in the skin, GI tract, and genitourinary tract, sclerotherapy has been adopted for lesions in various sites in the head and neck, but not for HHT. Case reports and one large series in the literature have described sclerotherapy for epistaxis due to HHT, but have not been followed by prospective studies …”

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confidence: 99%

Prospective randomized trial of sclerotherapy vs standard treatment for epistaxis due to hereditary hemorrhagic telangiectasia

Boyer

Fernandes

et al. 2015

Int Forum Allergy Rhinol

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Background Our previous studies have demonstrated the tolerability and low side-effect profile of office-based sclerotherapy with sodium tetradecyl sulfate (STS) for treating recurrent epistaxis due to hereditary hemorrhagic telangiectasia (HHT). The objective of this study was to use a prospective randomized trial to determine the effectiveness of sclerotherapy with STS vs standard treatment. Methods This prospective randomized trial (conducted from November 1, 2011, through January 31, 2014) involved 17 patients with recurrent epistaxis due to HHT. We defined standard treatment as continuation of any treatment that the patient had previously undergone, such as moisturization, packing, and cautery. We used a crossover design, so study participants were randomized to either sclerotherapy or standard treatment during the first time period, and then to the other during the second period. The primary outcome measure was frequency and severity of epistaxis, as measured by the epistaxis severity score (ESS). The ESS is a 10-point scale, with higher scores corresponding to more bleeding. Results After controlling for treatment order, bleeding was substantially better controlled after sclerotherapy; the ESS after sclerotherapy was nearly one point lower than after standard treatment (−0.95, 1-sided p = 0.027). Treatment order, baseline ESS, the number of lesions, moisturization practices, and a history of previous blood transfusions did not significantly affect the results. Conclusion This trial demonstrated that sclerotherapy with STS (vs standard treatment) significantly reduced epistaxis due to HHT.

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Retrospective analysis of facial paralysis caused by ethanol sclerotherapy for facial venous malformation

Hu¹,

Chen²,

Jiang³

et al. 2010

Head & Neck

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The use of foam sclerotherapy for the treatment of head and neck vascular malformations

Cited by 8 publications

References 3 publications

Office‐based sclerotherapy for recurrent epistaxis due to hereditary hemorrhagic telangiectasia: a pilot study

Office‐based sclerotherapy for recurrent epistaxis due to hereditary hemorrhagic telangiectasia: a pilot study

Prospective randomized trial of sclerotherapy vs standard treatment for epistaxis due to hereditary hemorrhagic telangiectasia

Retrospective analysis of facial paralysis caused by ethanol sclerotherapy for facial venous malformation

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