The use of flow perfusion culture and subcutaneous implantation with fibroblast-seeded PLLA-collagen 3D scaffolds for abdominal wall repair

Pu, Fanrong; Rhodes, Nicholas P.; Bayon, Yves; Chen, Rui; Brans, Gerben; Benne, Remco; Hunt, John A.

doi:10.1016/j.biomaterials.2010.02.010

Cited by 41 publications

(28 citation statements)

References 40 publications

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“…In each incision, 2 subcutaneous pockets were achieved using blunt dissection under aseptic conditions [13,23]. Each pocket placed a piece of flat film or a spiral stent at random.…”

Section: Subcutaneous Implantationmentioning

confidence: 99%

Autologous urothelial cells transplantation onto a prefabricated capsular stent for tissue engineered ureteral reconstruction

Xu¹,

Fu²,

Li³

et al. 2012

J Mater Sci: Mater Med

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In this study, we have fabricated an artificial ureter by transplantation of in vitro-expanded urothelial cells onto an in vivo-prefabricated capsular stent using tissue engineering methods. Spiral poly (L-lactic acid) (PLLA) stents were transplanted into the subcutaneous of Wistar rats for a period of 1, 2 or 3 weeks to induce the formation of connective tissue capsules on their surfaces. The capsular PLLA stents were then decellularized and further recellularized with bladder epithelial cells to fabricate artificial ureters. The results showed that the entrapped cells in all capsules remained continuously proliferation and lined up in continuous layers. In addition, the urothelial cells on the capsular stents with an embedding period of 2 or 3 weeks showed higher proliferative viability compared with the cells on the stents with an embedding time of 1 week (P < 0.05). The results of the study indicated that the prefabricated capsular stents could serve as alternative cell carriers for tissue engineered ureters, especially with embedding time from 2 to 3 weeks.

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“…In each incision, 2 subcutaneous pockets were achieved using blunt dissection under aseptic conditions [13,23]. Each pocket placed a piece of flat film or a spiral stent at random.…”

Section: Subcutaneous Implantationmentioning

confidence: 99%

Autologous urothelial cells transplantation onto a prefabricated capsular stent for tissue engineered ureteral reconstruction

Xu¹,

Fu²,

Li³

et al. 2012

J Mater Sci: Mater Med

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“…Las matrices más utilizadas se corresponden con matrices de dermis porcina (Permacol), dermis de cadáver humano (Alloderm, matriz dérmica acelular derivada humana), dermis bovina y otras (colágeno, etc.) (21)(22)(23)(24)(25).…”

Section: Figura 1 Ejemplo De Una Malla Abdominal Infectada (8)unclassified

Untitled

2015

Actual. Med.

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“…Such systems allow sustained cells existence compared to the neat PLLA. Polymer scaffolds coated with collagen [44] have been applied in bone regeneration, and renewal of blood vessels and nerves [14]. Similarly, fibres and disks of cellulose-graft-L-lactide copolymers with different lengths of grafted PLLA have been prepared [45].…”

Section: Application Of Biodegradable Polymers In Tissue Engineeringmentioning

confidence: 99%

“…Hybrid systems constructed of materials of both, natural and synthetic origins have comprised combined properties including mechanical and degradation properties, reproducibility in manufacturing, as well as application of simple fabrication techniques characteristic for synthetic polymers and the specific biological activity of natural materials [42][43][44]. Thus, coatings of hydroxyapatite at the surface of porous PLA enhance the cells adhesion to the matrix [42] and promote their migration in the composite material.…”

Section: Application Of Biodegradable Polymers In Tissue Engineeringmentioning

confidence: 99%

Biodegradable polymers suitable for tissue engineering and drug delivery systems

Porjazoska-Kujundziski¹,

Chamovska²

2017

Zas Mat

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The use of flow perfusion culture and subcutaneous implantation with fibroblast-seeded PLLA-collagen 3D scaffolds for abdominal wall repair

Cited by 41 publications

References 40 publications

Autologous urothelial cells transplantation onto a prefabricated capsular stent for tissue engineered ureteral reconstruction

Autologous urothelial cells transplantation onto a prefabricated capsular stent for tissue engineered ureteral reconstruction

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Biodegradable polymers suitable for tissue engineering and drug delivery systems

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