The Use of Epidural Buprenorphine for the Treatment of Postoperative Pain

Rondomanska, M.; Castro, J. De; Lecron, L

doi:10.1007/978-3-642-68261-2_16

Cited by 15 publications

(3 citation statements)

References 3 publications

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“…[14] The onset of action of epidural buprenorphine is found to be about 15 min. with maximum effect at 30 min (Rondomanska, 1982), [15] if given at the end of operation patient may have a painful part of period till the drug start its action. To prevent this Buprenorphine was given along with local analgesic drug to have continuous pain free period form beginning of surgery.…”

Section: Pain Scoringmentioning

confidence: 99%

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Effectiveness of Mixture of Xylocaine, Bupivacaine and Buprenorphine for Lumbar Blockade by Epidural Approach

Mavani

Patel

2019

AAN

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Background: Pain is one of the most compelling experience for human beings. Pain is the most difficult one to define and assess, as it is a purely subjective sensation experienced only by the sufferer. Present study was done in which Buprenorphine was given epidurally along with Bupivacaine and Xylocaine as a single shot technique to evaluate its potency, duration of analgesia and other side effects. Subjects and Methods: Fifty adult patients of ASA risk I/II undergoing lower abdominal surgery, lower limb-orthopaedic surgery, surgery involving perineal region and gynaecological procedures were selected for our study. The patients were divided into two groups consisting of 25 patients each. In group I, patients were given Inj. Bupivacaine 0.5% 20 cc + xylacaine in lumbar epidural space. In group II, patients were given Bupivacaine 0.5% 20 cc + xylacaine 0.5% 20 cc mixed with Inj. Buprenorphine 0.2 mg (2 ml) in same syringe in lumbar epidural space. Duration of total analgesia was measured with help of pain scorre, which were measured throughout operative period and in postoperative period. All the statistical tests will be performed in SPSS version 15 software. Results: In study group majority patients complain of pain at around 16 to 20 hours. Most of the patients in group-I are in 0-4 hours and in group-II are 20-24 hours. Maximum respiratory depression was around 12% (2/min). It was observed that hypotension was seen in 4 cases and bradycardia in 4 cases-intraoperatively and postoperatively no patient had bradycardia or hypotension in study group. Conclusion: Buprenorphine if given epidurally along with local anesthetic solution for various surgical procedures can provide excellent pain free period lasting up to 24 hours without any disturbances to normal physiology life and notable side effects.

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Section: Pain Scoringmentioning

confidence: 99%

“…S. Chakraborty (1984) [8] used 0.3 mg. Buprenorphine by epidural route and found analgesia upto 20 hrs. Rondomanska (1982), [15] used 0.3 mg. Buprenorphine and got painfree period for about 24 hours. Gudy A.R.…”

Section: Pain Scoringmentioning

confidence: 99%

Effectiveness of Mixture of Xylocaine, Bupivacaine and Buprenorphine for Lumbar Blockade by Epidural Approach

Mavani

Patel

2019

AAN

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“…Its activity is such that in nearly all clinical situations it is as effective an analgesic as morphine (2-4). Epidural buprenorphine has also been shown to provide a good postoperative analgesia after caesarean section (5)(6)(7)(8)(9).…”

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confidence: 99%

Spinal Buprenorphine for Postoperative Analgesia After Caesarean Section

Celleno¹,

Capogna²

1989

Obstetric Anesthesia Digest

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Two doses of intrathecal buprenorphine for postoperative analgesia have been compared. Forty-five women undergoing elective caesarean section under spinal anaesthesia were randomly divided into three groups.Group A (controls, n = 15) received hyperbaric bupivacaine; Groups B and C received the same but with the addition of 0.03 mg or 0.045 mg buprenorphine, respectively. Patients receiving buprenorphine had a longer pain-free interval than the controls ( P < 0.01). Within the buprenorphine groups, patients receiving the higher dose had a longer effect (420 min s.d. 24) than those receiving the lower dose (173 min s.d. 31) ( P < 0.01) without any increase in side-effects.

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The Effects of Intrathecally Administered Opioid and Adrenergic Agents on Spinal Function

Yaksh

1986

Spinal Afferent Processing

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The Use of Epidural Buprenorphine for the Treatment of Postoperative Pain

Cited by 15 publications

References 3 publications

Effectiveness of Mixture of Xylocaine, Bupivacaine and Buprenorphine for Lumbar Blockade by Epidural Approach

Effectiveness of Mixture of Xylocaine, Bupivacaine and Buprenorphine for Lumbar Blockade by Epidural Approach

Spinal Buprenorphine for Postoperative Analgesia After Caesarean Section

The Effects of Intrathecally Administered Opioid and Adrenergic Agents on Spinal Function

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