The use of enucleation and liquid nitrogen cryotherapy in the management of odontogenic keratocysts

Schmidt, Brian L.; Pogrel, M. Anthony

doi:10.1053/joms.2001.24278

Cited by 147 publications

(87 citation statements)

References 16 publications

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“…These include marsupialisation of the cyst or decompression followed by secondary enucleation, but results are in long term are ineffective [3]. Other procedures include surgical excision of the keratocyst followed by cryotherapy or Carnoy's solution [19,21,22]. In this case surgical enucleation of all the cystic lesions was done followed by removal of 1-2 mm layer of bone around the periphery of cystic cavities with sharp curette or a bone bur with sterile irrigation to remove the epithelial remnants, which could proliferate into recurrence of the cyst [13].…”

Section: Discussionmentioning

confidence: 99%

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Gorlin’s syndrome — Report of a case and management of cystic lesions

Anehosur

2009

J. Maxillofac. Oral Surg.

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Gorlin's syndrome associated with multiple cystic lesions is a rare and uncommon condition. It is characterized by cutaneous basal cell carcinomas, multiple keratocysts in the jaw bones and skeletal anomalies. A case is presented with multiple odontogenic keratocyst and dentigerous cysts occurring in all quadrants of oral cavity with features suggestive of Gorlin's Syndrome. The clinical presentation and the management of these multiple cystic lesions and a two year follow up study is presented.

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Section: Discussionmentioning

confidence: 99%

“…Various combination of treatments have been proposed i.e. surgical excision followed by cryotherapy or application of Carnoy's solution [21,19]. It has been suggested that the recurrence rate in patient's with Gorlin's syndrome may be higher than of cyst occurring in healthy individuals.…”

Section: Introductionmentioning

confidence: 99%

Gorlin’s syndrome — Report of a case and management of cystic lesions

Anehosur

2009

J. Maxillofac. Oral Surg.

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“…In our study, none of the patients who underwent resection reported recurrence of the cyst. Schmidt and Pogrel [22] found that 85.5 % of the patients showed no evidence of the clinical or radiographic recurrence after they were treated with enucleation and cryosurgery. In our study, four out of nine cases of treatment using the enucleation process showed recurrence and only one out of three patients treated with enucleation followed by fixation with Carnoy's solution showed signs of recurrence.…”

Section: Discussionmentioning

confidence: 99%

Treatment of Keratocystic Odontogenic Tumours: A Prospective Study of 30 Cases

Gupta¹,

Bansal²,

Sharma³

et al. 2016

J. Maxillofac. Oral Surg.

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Aim This prospective study aimed at presenting different treatment modalities and its association with the recurrence rate of KCOT. Material and Method The study was conducted on 30 patients diagnosed with KCOT between March 2009 and 2012. The patients were followed up for a period of at least 1 year. The clinical, radiographic and demographic data were recorded and four different treatment modalities were followed to assess the recurrence of the tumour. Results In the study, KCOT showed male predominance with a male: female ratio of 23:7. Of the total cases, 26 (86.67 %) patients had parakeratinised KCOT and the rest 4 (13.3 %) patients had orthokeratnised KCOT. Nine (30 %) patients were reported with recurrence of the tumour within 1-2 years of surgery-all these patients had parakeratinised cyst. Recurrence was observed in four (50 %) out of eight cases of marsupialisation and four (44.44 %) out of nine cases of treatment using the enucleation process. No recurrence was seen in patients treated with resection; however only one out of three patients treated with enucleation, followed by fixation with Carnoy's solution showed signs of recurrence. The histopathological examination determined the aggressive nature of KCOT and its association with the recurrence rate as well. The findings of our study indicate that more aggressive treatment can aid in reducing the chances of recurrence.

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“…The goal of both techniques was to kill epithelial remnants and dental lamina in the osseous margin. Carnoy's solution (absolute alcohol 6 mL, chloroform 3 mL, glacial acetic acid 1 mL, ferric chloride 1 gm) is a tissue fixative that penetrates bone to a depth of 1.54 mm [6,21,22]. The penetration and margin of cellular necrosis produced by liquid nitrogen cryosurgery in the mini pig model was shown to be average of 0.82 mm (0.51-1.52 mm) [23].…”

Section: Discussionmentioning

confidence: 99%

“…Recommended treatments have included curettage with peripheral ostectomy [5], curettage plus liquid nitrogen cryotherapy [6], curettage plus application of Carnoy's solution [7], localized en bloc resection [8,9], and occasionally mandibular segmental resection [8]. Some authors have stated that they should be regarded as benign cystic neoplasms and treated accordingly [10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

The Use of Enucleation and Chemical Cauterization (Carnoy’s) in the Management of Odontogenic Keratocyst of the Jaws

Rao

Kumar²

2012

Indian J Otolaryngol Head Neck Surg

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The purpose of this study was to evaluate the use of enucleation and chemical cauterization in the management of odontogenic keratocyst (OKC) of the jaw. This study involves the retrospective review of 32 patients (20 males and 12 females) with 34 biopsy proven odontogenic keratocysts. All patients received a combination of enucleation and chemical cauterization with every time freshly prepared Carnoy's solution (absolute alcohol 6 mL, chloroform 3 mL, glacial acetic acid 1 mL, ferric chloride 0.1 gm/mL). None of these patients were diagnosed with basal cell nevus syndrome. Four of these patients did not give the follow up and were not included in the study. A total of 30 biopsy proven OKC were resolved with this treatment method. Postoperative follow up consists of clinical and radiographic examination. Follow up time ranged from a minimum of 2 years to a maximum of 5 years. Mean follow up was of 2.8 years. Recurrence rate of 5.8% was observed. Hence, concluded that the combination of enucleation and chemical cauterization may offer patients improved therapy in the management of odontogenic keratocysts of the jaws.

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The use of enucleation and liquid nitrogen cryotherapy in the management of odontogenic keratocysts

Cited by 147 publications

References 16 publications

Gorlin’s syndrome — Report of a case and management of cystic lesions

Gorlin’s syndrome — Report of a case and management of cystic lesions

Treatment of Keratocystic Odontogenic Tumours: A Prospective Study of 30 Cases

The Use of Enucleation and Chemical Cauterization (Carnoy’s) in the Management of Odontogenic Keratocyst of the Jaws

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