The use of cyanoacrylate sealant as simple mesh fixation in laparoscopic ventral hernia repair: a large animal evaluation

Abstract

Using a standardized biomechanical testing system, synthetic glue can be considered an effective fixation tool in LVHR. The possible tissue toxicity of cyanoacrylates does not lead to an increased FBR. No difference in burst strength was observed for closing or not closing the defect.

Therapeutic Ureteral Occlusion with Ifabond Cyanoacrylate Glue: An Interesting Solution

“…Our choice was to use a synthetic glue, a cyanoacrylate-based polymer (CA), which has shown to provide high adhesion strength and is cheaper than biological glues (8). In the last years, cyanoacrylates have found application in several medical fields, from surgical wound closure to hemostasis of bleeding gastric varices, interventional radiology, and ophthalmology (8, 9). They have shown adhesive, bacteriostatic, and hemostatic qualities, together with a good profile of safety and biocompatibility (10).…”

Self-adhesive hydrogel meshes reduce tissue incorporation and mechanical behavior versus microgrips self-fixation: a preclinical study

“…Alternatively, either natural or synthetic adhesives applied to the receptor tissue bed are used as a common alternative for mesh fixation [30][31][32]. Some of these medical adhesives have already been evaluated by our research group in preclinical studies with very promising results, especially using long-chain CA, which considerably reduces tissue toxicity and shows quite good biological and mechanical behavior in the hernia repair process [24,33].…”

Factors Determining Outcome After Surgery for Chronic Groin Pain Following a Lichtenstein Hernia Repair

“…Inguinodynia is an untoward and incapacitating complication of herniorrhaphy that affects more than 10 % of the patients following standard open mesh repair [1]. This percentage is likely an underestimation as the majority of patients suffering from persistent pain is not referred for additional therapy [2][3][4]. Moreover, surgeons and residents also report that the incidence of persistent groin pain following open repair is probably rated too low [5].…”