The use of convex probe endobronchial ultrasound-guided transbronchial needle aspiration in a pediatric population: A multicenter study

Abstract

We report the first multicenter study to date confirming the feasibility and utility of EBUS-TBNA in the pediatric population. Due to the low overall procedural risk of EBUS-TBNA, it should be considered as a potential first line diagnostic option for children presenting with mediastinal or hilar abnormalities but further prospective studies are needed.

Endobronchial ultrasound‐guided transbronchial needle aspiration for diagnosing mediastinal lymphadenectasis: a cohort study from a single center

“…There were only three patients less than 18 years old. However, Gilbert et al (7) confirmed that it was feasible for pediatric patients who underwent EBUS-TBNA. There were 83 (9.8%) patients more than 70 years old who stayed safe with EBUS-TBNA.…”

ERS statement: interventional bronchoscopy in children

“…Adequate sampling can be achieved in 95% of cases, although diagnostic yield may only be 47%. The complication rate in children appears to be very low [65][66][67][68].…”

“…Although a 6.9-mm diameter puncturescope can be passed through a 2.5 laryngeal mask airway (LMA), ventilation is limited and a 4.0 LMA is preferable. EBUS TBNA can be performed under either general anaesthesia or sedation, and is generally well tolerated in children aged ⩾9 years [68]. Adequate sampling can be achieved in 95% of cases, although diagnostic yield may only be 47%.…”

A toddler with a cough and wheeze refractory to treatment

“…Gilbert et al 2 reviewed 21 paediatric patients who underwent EBUS TBNA using a specially designed bronchoscope equipped with a distal ultrasound probe allowing real-time ultrasound imaging at the time of biopsy (performed via operating channel). No significant adverse events were reported.…”

“…There was no difference in diagnostic yield between EBUS TBNA and EUS-B-FNA with a calculated diagnostic sensitivity of 79.1% for EBUS TBNA or EUS-B-FNA. One issue with EBUS TBNA identified in adults is the relatively high false-negative rate of needle aspirates in diagnosing lymphomas with prominent fibrosis and a mixed cellular population 2. This limitation is important to take into account in paediatric practice, given the higher incidence of lymphoma.…”