The Use of Coffee, Chewing-Gum and Gastrograffin in the Management of Postoperative Ileus: A Review of Current Evidence

Flores-Funes, Diego; Campillo-Soto, Álvaro; Pellicer-Franco, Enrique; Aguayo-Albasini, José Luís

doi:10.1016/j.cireng.2016.11.003

Cited by 9 publications

(7 citation statements)

References 41 publications

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“…Another problem with interpretation of such studies are that they are quite heterogeneous, there is a variable definition of POI ranging from 2 to 7 days by different authors, and this leads to non-reproducibility of studies and difficulties in interpreting the results. 1,20 Success of ERAS protocols (minimally invasive surgery, goal-directed fluid management, opioid-sparing analgesia, early mobilisation, early postoperative food intake, laxative administration, and omission/early removal of NG tube, drains and catheter) in elective abdominal surgery settings led to their use in emergency settings; they were associated with favourable outcomes as indicated by reduced postoperative complications, accelerated recovery of bowel function and shorter postoperative hospital stay without increasing need for re-admission or re-operation. 21 These benefits have been seen in many studies involving perforation peritonitis and intestinal obstruction and have now become part of standard guidelines.…”

Section: Discussionmentioning

confidence: 99%

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Effect of chewing gum in reducing postoperative ileus after gastroduodenal perforation peritonitis surgery: A prospective randomised controlled trial

Muwel,

Suryavanshi,

Damde

et al. 2024

Trop Doct

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Chewing gum reduces the duration of postoperative ileus and early recovery of bowel function following elective abdominal surgery. However, its role has not been studied in cases of gastroduodenal perforation peritonitis, prompting us to conduct this study. Patients were randomised into two groups, 39 patients received chewing gum (study group) and 43 patients were in the control group. Sensation of hunger, appearance of first bowel sound, and passages of flatus and faeces were significantly early in the study group; their hospital stay was also shorter. Chewing gum reduces the duration of postoperative ileus in cases of gastroduodenal perforation peritonitis. Registration number: IEC/2020-23/3359 dated 13 December 2020, Institutional Ethics Committee, Netaji Subhash Chandra Bose Medical College, Jabalpur, India.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Effect of chewing gum in reducing postoperative ileus after gastroduodenal perforation peritonitis surgery: A prospective randomised controlled trial

Muwel,

Suryavanshi,

Damde

et al. 2024

Trop Doct

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“…GG may be administered per oral or as an enema and is used routinely in clinical practice. Its safety has been established in a number of randomized trials [ 12 ]. A meta-analysis of contrast enemas found that procedures involving GG were safe with only 1 reported complication of the 1,169 procedures studied.…”

Section: Methodsmentioning

confidence: 99%

A development study of drain fluid gastrografin as a biomarker of anastomotic leak

et al. 2022

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Anastomotic leakage is the anathema of colorectal surgery. Its occurrence leads to increased morbidity and mortality and a prolonged hospital stay. Much work has gone into studying various biomarkers in drain fluid to facilitate early detection of anastomotic leak (AL). This 2a development study aims to assess the safety and feasibility of reliably detecting the iodine in Gastrografin (GG) in drain fluid and stool samples by Dual-Energy Computed Tomography (DECT). Methods This is a prospective, observational, controlled, consecutive cohort study establishing the safety and feasibility of the detection of GG in surgical drain fluid and stool as a biomarker of anastomotic leak when patients with a low pelvic colorectal anastomosis undergo luminal flushing of the rectal tube with GG. Results Ten consecutive patients were allocated to the saline flush group and the following ten to the GG flush group. Three patients in the saline flush group developed an AL. One patient in the GG flush group developed an AL. An elevation in the drain fluid GG was detected using DECT on the day of clinical deterioration. None of the patients in the control group were found to have a positive result on DECT. Conclusions This observational 2a development study demonstrates the safety of a novel approach to the early detection of AL from extraperitoneal colorectal anastomoses. The technique requires validation in a larger cohort and a multicentre study is planned to investigate the efficacy of GG rectal tube flushes as an early biomarker of AL in low pelvic anastomoses. What does this paper add to the literature? This paper assesses rectally administered Gastrografin (GG) as a novel drain fluid biomarker of anastomotic leak (AL). Few studies have investigated the extravasation of intraluminal substances. Intuitively, these are more likely to lead to the diagnosis of AL verses those that simply predict the possibility of a leak.

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“…It is well known that adequate perioperative nutritional status is important to prevent of postoperative ileus, along with short limitation of preoperative fasting to 6 hours for solid food and 2 hours for liquids. Coffee and chewing gum are also known to have preventive effect for postoperative ileus (57). With the utilization of these measures to prevent postoperative ileus, en bloc pelvic resections with rectosigmoid colectomy can be safely performed in patients with advanced EOC.…”

Section: Prolonged Ileus After Surgerymentioning

confidence: 99%

En bloc pelvic resection of ovarian cancer with rectosigmoid colectomy: a literature review

2021

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Maximal cytoreductive surgery is an important prognostic factor in advanced epithelial ovarian cancer (EOC). To achieve maximal cytoreductive surgery, en bloc pelvic resection with rectosigmoid colectomy can be an effective surgical strategy. This surgical methodology was first described in 1968 as "radical oophorectomy." Since then, it has been adopted by many medical institutions around the world, and its safety has been shown by many studies. However, research on the surgical method is still lacking due to the limited number of prospective comparative studies. We will review the journals on en bloc pelvic resection with rectosigmoid colectomy published to date and discuss its efficacy, complications, and surgical techniques of the procedures.

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The Use of Coffee, Chewing-Gum and Gastrograffin in the Management of Postoperative Ileus: A Review of Current Evidence

Cited by 9 publications

References 41 publications

Effect of chewing gum in reducing postoperative ileus after gastroduodenal perforation peritonitis surgery: A prospective randomised controlled trial

Effect of chewing gum in reducing postoperative ileus after gastroduodenal perforation peritonitis surgery: A prospective randomised controlled trial

A development study of drain fluid gastrografin as a biomarker of anastomotic leak

En bloc pelvic resection of ovarian cancer with rectosigmoid colectomy: a literature review

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