The Use of Cerebral Oximetry in Acute Carbon MonoxideIntoxication

Abstract

The purpose of this study was to assess the clinical usefulness of near-infrared spectroscopy (cerebral oximetry) in patients presenting to the emergency department (ED) with carbon monoxide (CO) intoxication. Eighteen patients with a diagnosis of CO intoxication who presented to our ED during 2013 were included in this prospective study. All patients were treated and monitored according to the standard recommendations for CO intoxication. In addition, cerebral oxygen saturation (ScO 2 ) was measured using near-infrared spectroscopy, also known as cerebral oximetry. Minimum and maximum ScO 2 values from the right and left frontal region were recorded using cerebral oximetry from immediately after presentation to the ED until discharge. Patient blood carboxyhemoglobin (COHb) levels before and after oxygen treatment were compared with the cerebral oximetry measurements. At the time of admission, mean blood (COHb) values were 29.3% ± 6.7%, and ScO 2 values were 59.0 ± 4.0 in the right frontal region and 60.9 ± 5.1 in the left. When blood COHb levels had returned to normal following oxygen therapy, ScO 2 values were 75.9 ± 6.1 (65.5-90.5) in the right frontal region and 74.9 ± 7.8 (62.0-90.0) in the left. The differences in ScO 2 values before and after oxygen therapy were statistically significant (P ≤ 0.005). Assessment of patients exposed to CO gas using cerebral oximetry can provide information about cerebral oxygen saturation. Blood COHb level measurement is still the best method for diagnosing CO intoxication; however, cerebral oximetry, a non-invasive technique, may be an effective method for assessing cerebral oxygen saturation.

Association Between Near Infrared Spectroskopy (NIRS) and Normobaric and Hyperbaric Oxygen Treatment in Acute Carbon Monoxide Poisoning

“…In the study conducted by Kalkan et al again with INVOS-5100 NIRS device, the pre-treatment ScO2 levels were found to be low and the ScO2 levels after treatment were found to be significantly higher in CO intoxicated patients given NBOT in emergency services. (13). We also found in our study that similar to that of Kalkan et al, but in contrast to Niemann et al's study, the average ScO2 levels of patients treated with NBOT were higher than those of before treatment.…”

Cerebral Oximetry and Applications Under Anesthesia

“…Verici dioddan çıkan ışınların alıcı diodlarca algılanması temelinde çalışır. Yani oksijenize hemoglobin ile deoksijenize hemoglobin oranını değerlendirmektedir (8). Oksimetre, dokudaki yakın kızılötesi spektrumdaki ışığın iletimi ve kromoforlarla emilimine dayanır.…”

A new technique in the evaluation of strangulated and incarcerated hernias: Near infrared spectroscopy

“…Although there have been many studies of brain tissue oxygenation, the use of NIRS in assessing oxygenation of the intra-abdominal organs and intestines is particularly noteworthy. [2][3][4][5][6] In an experimental study by Gay et al, [7] which evaluated oxygenation of the intra-abdominal organs and intestines in piglets using NIRS, reduced blood flow was reported in the intestine and intra-abdominal organs in animals with induced hemorrhagic shock. No significant difference was determined between invasive methods and NIRS measurements.…”