The use of alpha‐2‐macroglobulin as a novel treatment for patients with chronic pelvic pain syndrome

Abstract

Synopsis Alpha‐2‐macroglobulin shows potential for use as an adjunctive treatment option for chronic pelvic pain syndrome when injected into Alcock’s canal using a hydrodissection technique.

Combination of Enzymes and Rutin to Manage Osteoarthritis Symptoms: Lessons from a Narrative Review of the Literature

“…Alpha-2 M Activation by Proteases Alpha-2 M is a plasma proteinase inhibitor with inflammatory properties that regulates the distribution and activity of many cytokines [58][59][60][61][62]. Though the exact mechanism is not known, animal models and human studies have demonstrated that proteolytic enzymes, such as trypsin and bromelain, are absorbed as physiologically intact molecules [63][64][65].…”

A physiatrist's understanding and application of the current literature on chronic pelvic pain: a narrative review

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