“…Ketamine, combined with guaifenesin, 16 lidocaine, 17 medetomidine, and guaifenesin 18 or medetomidine and benzodiazepines, 19 has been the drug most commonly used for this purpose. 24,25 For this reason, it could represent a useful adjunct to ketamine for PIVA in horses. 22,23 Among α 2 -adrenergic receptor agonists, romifidine provides longer lasting analgesia and less ataxia, compared with equipotent sedative doses of xylazine, detomidine, and romifidine.…”