“…Wear particles can generate a giant cell foreign body reaction with potential loosening of the implant, resulting in occlusal change or displacement or fracture. Other problems relate to long-term stability, cost, dystrophic bone formation, and lack of growth which precludes the use of such joints in children (Kent et al 1994, Mercuri et al 2000. Custom-made total joint prostheses for TMJ reconstruction , custom-made prosthesis, made with orthopaedically proven structural materials, in combination with autogenous peri-implant fat grafting significantly improved the predictability and success rates of treatment for the rehabilitation of complex TMJ patients with inflammatory diseases, connective tissue/autoimmune diseases, ankylosis, tumors, or absence of TMJ structures (Larry et al 2000 ) (Fig.…”