The use of 90% Aloe vera freeze drying as the modulator of collagen density in extraction socket of incicivus Cavia cobaya

Abstract

Wound healing is basically a complex process in which cellular and matrix act in concern to re-establish the integrity of injury tissues. This process can be simplified to be healing process consisted of haemostatic, inflammation, cell proliferation and tissue remodeling. The aimed of this research was to know the influence of freeze drying 90% Aloe vera application as mandible collagen density modulator in extraction socket of incisive Cavia cobaya. This research was done using Post Test Only Control Groups Design and Cavia cobaya as the sample. Six samples of each control group and 90% Aloe vera group applied to test each collagen density for three days and seven days. Then, the data was analyzed statistically using Mann Whitney with 5% significance rate. The result of the study indicates that administering 90% Aloe vera can accelerate the growth of collagen density in healing process of extraction socket. The conclusion is 90% Aloe vera can modulate the density of collageneous fiber in socket of extraction incicivus tooth wound of Cavia cobaya.

Comparative evaluation of subgingivally‐delivered 1% metformin and Aloe vera gel in the treatment of intrabony defects in chronic periodontitis patients: A randomized, controlled clinical trial

“…It had been used as a remedy of recurrent oral ulceration, oral lichen planus, oral candidiasis, over extraction socket, and as an endodontic medicament. Various dentrifices also contain AV gel as its constituents because of its medicinal property …”

Stimulation of osteoblast activity by induction of Aloe vera and xenograft combination

“…Cavia cabaya was taken and anaesthetized using inhalation anesthetic ether, with 1 ml/1kg weight dose, 8 then the incisive tooth was extracted. Post tooth extraction sockets were filled according to grouping and then stitched.…”

“…Aloevera is a natural material that is necessary to be tested for the safe extract dose used for this study. 8 It is needed to know whether the use of Aloe vera gel and xenograft cancellous bovine (XCB) combination on post tooth extraction sockets can accelerate the growth of alveolar bone, thus, it can prevent the occurrence of alveolar bone resorption. As a result, the making of artificial tooth can be conducted well.…”

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