The Use of 5‐Hydroxymethylfurfural (5‐HMF) in Multi‐Component Hantzsch Dihydropyridine Synthesis
Jingjing Jiang,
Yves Queneau,
Florence Popowycz
Abstract:The renewable 5‐hydroxymethylfurfural (5‐HMF) has gained a wide interest from the chemistry community as a valuable biobased platform opening the way to further functionalization. Despite an impressive number of publications reporting either its preparation or its functionalization, its direct use in fine chemistry, and especially in multi‐component reaction (MCR), is less reported. Here, we report a complete study of the use of 5‐HMF in the Hantzsch dihydropyridines synthesis. The strategy was applied to a sc… Show more
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