The Unsuspected Pelvic Factor in the Infertility Investigation

Drake, Terrance S.; Grunert, George M.

doi:10.1097/00006254-198102000-00020

Cited by 20 publications

(22 citation statements)

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“…Conclusions: These experiments confirm that SOD, diltiazem, and dexamethasone can decrease adhesion formation. The absence of effect from the other antiinflammatory drugs and anti-TNF-alpha is surprising.Postoperative adhesion formation remains an important clinical problem because it causes intestinal obstruction [1], chronic pelvic pain [2], female infertility [3], and difficulties at the time of reoperation. However, adhesion prevention still is inadequate and poorly understood overall.…”

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confidence: 99%

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Effect of reactive oxygen species scavengers, antiinflammatory drugs, and calcium-channel blockers on carbon dioxide pneumoperitoneum-enhanced adhesions in a laparoscopic mouse model

Binda

Molinas²,

Bastidas

et al. 2007

Surg Endosc

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mentioning

confidence: 99%

“…Postoperative adhesion formation remains an important clinical problem because it causes intestinal obstruction [1], chronic pelvic pain [2], female infertility [3], and difficulties at the time of reoperation. However, adhesion prevention still is inadequate and poorly understood overall.…”

mentioning

confidence: 99%

Effect of reactive oxygen species scavengers, antiinflammatory drugs, and calcium-channel blockers on carbon dioxide pneumoperitoneum-enhanced adhesions in a laparoscopic mouse model

Binda

Molinas²,

Bastidas

et al. 2007

Surg Endosc

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“…Endometriosis is an estrogen-dependent inflammatory process affecting 10% to 15% of fertile women, and as many as 50% of infertile women (1,2). The disease process is defined by the presence of hormone-responsive endometrial tissue outside of the uterine cavity.…”

Section: Discussion and Literature Reviewmentioning

confidence: 99%

Endometriosis causing lower extremity deep vein thrombosis — case report and review of the literature

Sharma¹,

Delly²,

Marin³

et al. 2009

Int J Angiol

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Endometriosis is a medical condition in women wherein endometrial cells deposited in the area outside the uterine cavity are influenced by hormonal changes, and produce symptoms depending on the site of implantation. A unique case of retroperitoneal endometriosis causing deep vein thrombosis from extrinsic compression of the right iliac vein is described. Clinical presentation with cyclical leg swelling, coincidental with menstruation and culminating with deep vein thrombosis, although very suggestive, has not been previously reported.

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“…More recent studies have reported a similar rate of endometriosis in infertility patients undergoing laparoscopy. This is in contrast to a less than 5% incidence of endometriosis in patients undergoing tubal ligation [4][5][6].…”

Section: Introductionmentioning

confidence: 95%

Endometriosis and Infertility: Is There a Cause and Effect Relationship?

Witz

Burns²

2002

Gynecol Obstet Invest

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An association between endometriosis and infertility has long been noted. Endometriosis affects approximately 5% of the general population. In infertile women, the prevalence may be as high as 30%. Multiple studies, the majority of which are retrospective, indicate that the monthly fecundity of patients with endometriosis may be decreased by half compared to women without the disease. The precise cause-effect relationship between endometriosis and infertility remains controversial. In advanced cases of endometriosis, with distorted pelvic anatomy, the mechanism of infertility is more easily explained. Recent evidence suggests that treatment of early-stage endometriosis may increase pregnancy rates. Many etiologies of infertility in early-stage endometriosis have been proposed. These include endocrine dysfunctions such as luteal phase defect and luteinized unruptured follicle syndrome. In the last 15 years, alterations in the local pelvic immune environment have been the subject of multiple basic science investigations. Unfortunately, there is no satisfactory hypothesis that unequivocally explains the association of early stages of endometriosis with infertility.

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The Unsuspected Pelvic Factor in the Infertility Investigation

Cited by 20 publications

References 0 publications

Effect of reactive oxygen species scavengers, antiinflammatory drugs, and calcium-channel blockers on carbon dioxide pneumoperitoneum-enhanced adhesions in a laparoscopic mouse model

Effect of reactive oxygen species scavengers, antiinflammatory drugs, and calcium-channel blockers on carbon dioxide pneumoperitoneum-enhanced adhesions in a laparoscopic mouse model

Endometriosis causing lower extremity deep vein thrombosis — case report and review of the literature

Endometriosis and Infertility: Is There a Cause and Effect Relationship?

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