The unmet global burden of COPD

Quaderi, Shumonta; Hurst, John R.

doi:10.1017/gheg.2018.1

Cited by 337 publications

(266 citation statements)

References 15 publications

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“…[5][6][7] The effects of air pollution on the respiratory system include increased respiratory symptoms, decreased lung function, and increased incidence of chronic cough and bronchitis. 8,9 Epidemiological and clinical studies show that in children and adults, increased hospital admissions, lung diseases, lung cancer, 10 bronchiectasis, [11][12][13][14] respiratory infection, pulmonary embolism, asthma, 2,6,[15][16][17][18] and chronic obstructive pulmonary diseases (COPD) 9,[19][20][21][22][23] are affected by air pollution.…”

Section: Introductionmentioning

confidence: 99%

<p>Acute Effects of Air Pollution on Hospital Admissions for Asthma, COPD, and Bronchiectasis in Ahvaz, Iran</p>

Raji¹,

Riahi²,

Borsi³

et al. 2020

COPD

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Background and Aim: Although air pollution is a serious problem in Ahvaz, the association between air pollution and respiratory diseases has not been studied enough in this area. The aim of this study was to determine the relation between short-term exposure to air pollutants and the risk of hospital admissions due to asthma, COPD, and bronchiectasis in Ahvaz. Methods: Hospital admissions data and air pollutants including O 3 , NO, NO 2 , SO 2 , CO, PM 10, and PM 2.5 were obtained from 2008 to 2018. Adjusted Quasi-Poisson regression with a distributed lag model, controlled for trend, seasonality, weather, weekdays, and holidays was used for data analysis. Results: The results showed a significant increase in hospital admissions for asthma (RR=1.004, 95% CI: 1.002-1.007) and COPD (RR=1.003, 95% CI: 1.001-1.005) associated with PM 2.5 . PM 10 was associated with increased hospital admissions due to bronchiectasis in both genders (Men: RR=1.003, 95% CI: 1.001-1.006) (Female: RR=1.003, 95% CI: 1.000-1.006). NO 2 was also associated with an increased risk of hospital admissions for asthma (RR=1.040, 95% CI: 1.008-1.074) and COPD (RR=1.049, 95% CI: 1.010-1.090). SO 2 was associated with the risk of hospital admissions of asthma (RR=1.069, 95% CI: 1.017-1.124) and bronchiectasis (RR=1.030, 95% CI: 1.005-1.056). Finally, CO was associated with COPD (RR=1.643, 95% CI: 1.233-2.191) and bronchiectasis (RR=1.542, 95% CI: 1.035-2.298) hospital admissions. Conclusion: Short-term exposure to air pollutants significantly increases the risk of hospital admissions for asthma, COPD, and bronchiectasis in the adult and elderly population.

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Section: Introductionmentioning

confidence: 99%

<p>Acute Effects of Air Pollution on Hospital Admissions for Asthma, COPD, and Bronchiectasis in Ahvaz, Iran</p>

Raji¹,

Riahi²,

Borsi³

et al. 2020

COPD

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“…Chronic obstructive pulmonary disease is a global health issue which is described as under-recognized, under-diagnosed and undertreated (Quaderi & Hurst, 2018). A 2006 systematic review and meta-analysis reported poor prevalence measurement, with a lack of good quality data from outside Europe and North America (Halbert et al, 2006).…”

Section: Backg Rou N Dmentioning

confidence: 99%

Interventions at presentation and discharge for patients with acute exacerbation of chronic obstructive pulmonary disease to reduce unnecessary admissions and readmissions: A scoping review protocol

2019

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Aim This scoping review will gather existing evidence on specific interventions at presentation and discharge which aim to standardize care and/or reduce unnecessary admissions and/or readmissions to hospital for patients presenting with acute exacerbation of chronic obstructive pulmonary (airways) disease. Design Scoping review of relevant literature from January 2000–March 2019. Methods Database searches for primary evidence in peer‐reviewed journals will be conducted electronically using Web of Science, EMBASE (Elsevier) and PUBMED. Eligibility criteria will include hospital‐based interventions for presentations of acute exacerbation of chronic obstructive pulmonary disease with outcomes specific to standardizing care or reducing unnecessary admissions or readmissions. Abstract, full‐text screening and data extraction will be completed independently by a panel of expert reviewers. Results We aim to identify current interventions and improvement approaches in acute exacerbation of chronic obstructive pulmonary (airways) disease care that have an impact on admission and discharge processes or readmissions. Recommendations as a result of this review will aid the design and development of future improvement intervention.

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“…Chronic obstructive pulmonary disease (COPD) has been a high burden to health systems globally for many years and continues to have unmet need . It is a heterogeneous condition with differing mechanisms of disease in different subsets of patients.…”

mentioning

confidence: 99%

“…Chronic obstructive pulmonary disease (COPD) has been a high burden to health systems globally for many years and continues to have unmet need. 1 It is a heterogeneous condition with differing mechanisms of disease in different subsets of patients. One development in recent years has been the identification of the peripheral blood eosinophil count as a simple, clinically accessible biomarker of a clinically important inflammatory phenotype of the condition: eosinophilic COPD.…”

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confidence: 99%