The Unique Nature of Depression and Anxiety among College Students with Adverse Childhood Experiences

Watt, Toni Terling; Ceballos, Natalie A.; Kim, Seoyoun; Xi, Peng; Sharma, Shobhit

doi:10.1007/s40653-019-00270-4

Cited by 27 publications

(15 citation statements)

References 55 publications

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“…In a preliminary study, we observed that while depressive symptoms did not relate to IL-6 levels, childhood trauma scores were positively associated with adult levels of this cytokine ( Franklyn and McQuaid, 2020 ). Similarly, individuals with depression and a history of childhood trauma displayed elevated inflammatory levels compared to controls, an effect not found among depressed individuals with no history of childhood trauma ( Danese et al., 2008 ; Watt et al., 2020 ). These data highlight the possibility that childhood trauma and inflammatory processes are linked to mental health disorders in a subset of individuals ( Danese and Lewis, 2017 ).…”

Section: Considering Context and Experiencesmentioning

confidence: 87%

Transdiagnostic biomarker approaches to mental health disorders: Consideration of symptom complexity, comorbidity and context

McQuaid

2021

Brain, Behavior, & Immunity - Health

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Depression is a multifaceted disorder characterized by heterogeneous symptom profiles and high rates of comorbidity with other commonly occurring mental illnesses. Considering the burden of mental health disorders and the lack of efficacy of available treatments, there is a need for biomarkers to predict tailored or personalized treatments. However, identifying reliable biomarkers for complex mental illnesses, such as depression, anxiety and PTSD, has been challenging, likely owing to the heterogeneity, comorbidity and differences in experiences and histories of individuals. For these reasons, taking a transdiagnostic approach, which identifies biomarkers that map onto shared symptoms/constructs across disorders could be most effective for informing personalized or precision medicine approaches in psychiatry. Transdiagnostic features of anxiety, depression and anhedonia have been examined in relation to brain activity and connectivity patterns. Neuroendocrine and inflammatory markers, which are altered in depression and other comorbid illness, such as post-traumatic stress disorder (PTSD), might be useful in differentiating transdiagnostic symptom profiles as well as treatment responses. Ultimately, biomarker research that looks beyond diagnostic categories and embraces the complexity of individuals' lives and experiences might be more effective in moving towards precision medicine in psychiatry.

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Section: Considering Context and Experiencesmentioning

confidence: 87%

Transdiagnostic biomarker approaches to mental health disorders: Consideration of symptom complexity, comorbidity and context

McQuaid

2021

Brain, Behavior, & Immunity - Health

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“…Lastly, the experience of early life adversity may influence health behaviours through its impact on mental health. Previous research with undergraduate student samples have found ACE to have a strong, graded relationship with mental health outcomes including depression, anxiety and self‐reported stress levels (Watt et al, 2019), processes that can alter information seeking and engagement behaviours (Shi, 2019) and the adoption of negative health behaviours (Forster et al, 2019). To better understand these relationships, longitudinal investigations are needed to determine if, and how, mental health modifies the observed relationships between ACE exposure and health behaviour.…”

Section: Discussionmentioning

confidence: 99%

“…In addition to developing strategies designed to mitigate the consequences of ACE on physical and mental health in college student populations (Forster et al, 2019; Merians et al, 2019; Watt et al, 2019), future research should consider incorporating health promotion initiatives that facilitate the uptake of positive health behaviours. For example, ACE‐exposed students were as or more likely to express interest in receiving health information from their university but significantly less likely to receive health information on most topics assessed.…”

Section: Discussionmentioning

confidence: 99%

Adverse childhood experiences and college student health promotion outcomes: Another perspective on the trauma‐health relationship

et al. 2022

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Most research to date has focused on negative health outcomes associated with adverse childhood experience (ACE) exposure. The goal of the present study was to examine the relationship between ACE exposure and health information seeking, health promoting behaviours and health screening among US college students. Supplemental ACE items were added to the cross‐sectional National College Health Assessment survey administered between 2017 and 2018 with young adult (ages 18–29) college students in California (n = 3862) and Texas (n = 451). Approximately 41.9 per cent of participants reported ACE. ACE‐exposed participants were consistently and significantly less likely to receive health information from their university (p < 0.01). Using multivariable logistic regression models, reporting four or more ACE was associated with significantly lower odds of past year seatbelt use (AOR = 0.62, 95% CI = 0.44–0.89) and past 30‐day condom use during oral sex (AOR = 0.51, 95% CI = 0.27–0.97). Increases in ACE exposure were significantly associated with an increase in the odds of ever testing for HIV (AORs:1.26–2.49). Longitudinal research is needed to uncover the complex interplay between ACE, mental health, negative health behaviours and health promotion activities among young adults. Interventions to improve health promotion activities in ACE‐exposed populations could improve health and quality of life for this vulnerable population. Key Practitioner Messages ACE exposure has a potentially harmful impact on health education efforts and health promotion outcomes including healthy behaviours and obtaining regular health screenings. Young adults with a history of ACE exposure are more likely to report HIV screenings and more work is needed to uncover the reason for this association. College campus health education and promotion programs should target ACE affected young adults.

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“…When the ability to tolerate or recover from negative emotions is weak, anxiety can be realized. It has been found that children who have had four or more ACEs are more likely to suffer from anxiety and depression than children who have not had these events [17].…”

Section: Ace and Anxietymentioning

confidence: 99%

Prevention of Mental Illnesses Caused by Adverse Childhood Experience

Huang¹

2021

Proceedings of the 2021 International Conference on Public Relations and Social Sciences (ICPRSS 2021)

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Adverse childhood experiences (ACEs) are potentially stressful events that children experience before the age of 18 years old. Numerous studies have linked negative health, as well as developmental and behavioral outcomes to the exposure of ACEs. This study analyzes existing research theories and results to discuss the relationship between ACE and mental health (such as depression, anxiety, and suicide). Findings provide support for a relationship between ACEs and the prospective risk of common mental illnesses. Some measures (Trauma informed care, Nurse-Family Partnership) may reduce stress-related burdens on children and adolescents, which could lead to improvements in their psychological complaints in adult period.

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The Unique Nature of Depression and Anxiety among College Students with Adverse Childhood Experiences

Cited by 27 publications

References 55 publications

Transdiagnostic biomarker approaches to mental health disorders: Consideration of symptom complexity, comorbidity and context

Transdiagnostic biomarker approaches to mental health disorders: Consideration of symptom complexity, comorbidity and context

Adverse childhood experiences and college student health promotion outcomes: Another perspective on the trauma‐health relationship

Prevention of Mental Illnesses Caused by Adverse Childhood Experience

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