“…A stronger emphasis on the socio-demographic disparities of the population within each unit encourages individual-level research, where the attributes are collected from individuals, and the socio-demographic attributes are employed to more precisely estimate the effect size of the impact on a health outcome [ 22 ]. Regarding individual-level research, the residence-based paradigm derives the environmental settings at people's home locations as their long-term and primary exposure [ 23 , 24 ], while the mobility-oriented paradigm further incorporates the complete activity spaces (both within and outside home locations) to mitigate the contextual errors in exposure measures [ 25 ]. Different research paradigms retain different assumptions of exposure measures and are suitable for different research questions.…”