The (Un)Necessary Use of Short-Tandem-Repeat (STR) Testing on Bone Marrow Samples in Patients After 1 Year Postallogeneic Hematopoietic Stem Cell Transplant
Abstract:Allogeneic hematopoietic stem cell transplant (HSCT) patients at our institution are monitored at multiple time points posttransplant for neoplastic disorders by short-tandem-repeat (STR) testing of unfractionated bone marrow (BM) and BM biopsy evaluation (morphology, flow cytometry, genetics) to assess for engraftment, rejection, relapse risk, graft-versus-host disease, and disease relapse. Since there is some overlap in the information provided by STR and BM biopsies, we asked if and when this combined testi… Show more
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