The ultrstructure of chemodectoma of the larynx

Atypical Carcinoid Tumor of the Larynx

“…The clinical and pathological data for 127 of these [1, are listed in table 1. Although data for individual cases were not supplied in the recent report of 41 cases by Milroy et al [57], infor mation regarding 5 of their cases had appeared in earlier publica tions [4,7,13,28,47], Four cases [10, 11 ; 16, 17; 24, 25; 44, 45] had been published twice; at least eight of the tumors [4,5,7,12,[26][27][28]33] had been reported earlier as paragangliomas (table 2); and seven LAC (supplied by Dr. Alfio Ferlito and Dr. James Woodruff) appear in print for the first time in this article (tables 1,3). Additional data obtained by communication with the authors or culled from the literature has been provided for many of these cases.…”

Paraganglioma ofthe Supraglottic Larynx

“…3 years Azevedo-Gamas and Gloor [20] 36, F supraglottis lateral pharyngotomy NED, 0.5 year Vetters and 60. M supraglottis partial laryngectomy cervical métastases: too short Toner [21] and RND follow-up after excision Ishida et al [22] 19, M supraglottis supraglottic laryngectomy too short follow-up Adlington and 72, M supraglottis partial laryngectomy, RND, regional, skin, inner organ Woodhousc [23] irradiation (6.000 rad) métastases; DOD, 5 years Hooper [24] 55, M supraglottis excision via laryngoscopy, massive metastatic spread; irradiation (5,400 rad). RND DOD.…”

“…Despite similar ultrastruc ture of the laryngeal paraganglia and those occurring elsewhere, no chemorcceptor ac tivity has been noted for the laryngeal para ganglionic tissue [21,23]. Application of the term chemodectoma to tumors arising from the laryngeal paraganglia, therefore, seems premature.…”

“…Over half of the patients reported un derwent conservative laryngeal surgical pro cedure such as: excision via laryngofissure, via lateral pharyngotomy, supraglottic or hemivertical laryngectomy (table I). Total la ryngectomy alone or combined with radical neck dissection has been sometimes per formed [14,19,23,26,30], but these proce dures are probably not warranted unless an excessively large tumor or malignant disease is present. Preoperative selective angiogra phy and arterial embolization through the superior thyroid artery was performed in 2 cases [34,35], Irradiation therapy for para ganglioma of the head and neck is controver sial.…”

Paraganglioma of the Larynx

“…A review of the world literature through April 1990 has revealed at least 81 cases of alleged paragangliomas of the larynx including the two in this report , Some of these have been reported in more than one pub lication [1,14,16,20,21,23,25,34,39,45,52,61,64,70,74], Wenig and Gnepp [80] also mention eight addi tional cases that are contained in the Armed Forces Insti tute of Pathology -Otolaryngology Registry, but since no further details are provided, they are not included. In three instances, the publication could not be obtained and had to be excluded [9,17,28].…”