The UFAW handbook on the care and management of laboratory animals, 6th edn

Donnelly, Harriet

doi:10.1016/0007-1935(88)90055-3

Cited by 6 publications

(1 citation statement)

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“…Accounting for thermoregulatory effects was not considered necessary in this paper but will be in future studies. In this study, the temperature of blood, T b , was chosen to be 37 • C (as supported by Poole 1987), and the ambient air temperature, T a , was set to 20 • C. The convection coefficient h was chosen to be 10.5 W m −2 • C −1 as in Wang and Fujiwara (1999). McIntosh et al (2005) gives further details on these parameters.…”

Section: Computational Modelling Setupmentioning

confidence: 99%

Comparison of radiofrequency exposure of a mouse dam and foetuses at 900 MHz

et al. 2010

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In vivo studies involving radiofrequency (RF) exposure of rodents require detailed dosimetric analysis to enable correct interpretation of biological outcomes. Detailed anatomical models of mice--a female, a pregnant female, a male and a foetus--have been developed for analyses using finite difference numerical techniques. The mouse models, consisting of 49 tissues, will be made freely available to the research community. In this note, the pregnant mouse model, which included eight mature foetuses, was utilized specifically to consider (a) the RF dosimetry in a radial cavity exposure system operated at a frequency of 900 MHz and (b) a 900 MHz plane wave exposure. A comparison was made between the exposure of the mouse dam and the foetuses as specified by the specific energy absorption rate (SAR) and the resultant temperature change. In general, the SAR levels in the foetuses were determined to be slightly lower (around 14% lower than the average values of the dam) and the peak temperature increase was significantly lower (45%) than the values in the dam.

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Section: Computational Modelling Setupmentioning

confidence: 99%

Comparison of radiofrequency exposure of a mouse dam and foetuses at 900 MHz

et al. 2010

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The effect of stress on semen reduction in the marmoset monkey (Callithrix jacchus)

Cui

1996

Human Reproduction

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This study compared a number of semen parameters of two separate groups of the common marmoset monkey (Callithrix jacchus) in order to determine the effect of a continuous potentially stressful situation on these parameters, and thus on the monkey's reproductive ability. The semen from 16 adult male marmoset monkeys was collected and analysed to compare semen parameters between a 'normal' (control) group (n = 9) and a 'blood withdrawn' ('stress') group (n = 7). The semen parameter values observed in the control were: pH 7.51 +/- 0.22, volume 40.2 +/- 27.2 microliters, concentration 27.3 +/- 14.8 x 10(4)/microliters, motility 47.4 +/- 15.9%, grade of velocity 3.5 +/- 1.2, and normal morphological forms 51.8 +/- 13.7%. The 'blood withdrawn' group of marmoset monkeys showed significantly lower semen volume and sperm concentration than the 'normal' group. In addition, total count of spermatozoa, normal spermatozoa, motile spermatozoa and normal motile spermatozoa per ejaculate per monkey was significantly reduced in the 'blood withdrawn' group. The semen of these monkeys also revealed a significantly higher percentage of abnormally-shaped sperm heads than the normal group, and cases of impotence and sham ejaculation were recorded. Our study revealed that the continuous withdrawal of a small volume of blood from a group of marmoset monkeys appeared to be stressful to these monkeys and as a result, influenced their semen parameters, possibly making them less fertile. In addition, electroejaculation was found to be possibly harmful to the monkey's reproductive ability.

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