The Typology of Metabolic Syndrome in the Transition to Adulthood

Stanley, Takara L.; Chen, Minghua L; Goodman, Elizabeth

doi:10.1210/jc.2013-3531

Cited by 22 publications

(22 citation statements)

References 40 publications

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“…10, 33 -35 Large proportions of children defined as having MetS during childhood do not meet the diagnostic criteria on follow-up 3 to 6 years later. 10,34 In multiple observational longitudinal studies, although population-level prevalence has increased, withinperson variation in presence or absence of MetS has been large, with many studies showing 50% or more of MetS-positive subjects becoming MetS-negative over time, whether that be with short-term (∼3 weeks) 36 or longer-term (9 years) 35 follow-up. The instability was not related to change in weight status.…”

Section: Defining Mets In Pediatricsmentioning

confidence: 99%

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The Metabolic Syndrome in Children and Adolescents: Shifting the Focus to Cardiometabolic Risk Factor Clustering

2017

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Metabolic syndrome (MetS) was developed by the National Cholesterol Education Program Adult Treatment Panel III, identifying adults with at least 3 of 5 cardiometabolic risk factors (hyperglycemia, increased central adiposity, elevated triglycerides, decreased high-density lipoprotein cholesterol, and elevated blood pressure) who are at increased risk of diabetes and cardiovascular disease. The constellation of MetS component risk factors has a shared pathophysiology and many common treatment approaches grounded in lifestyle modification. Several attempts have been made to define MetS in the pediatric population. However, in children, the construct is difficult to define and has unclear implications for clinical care. In this Clinical Report, we focus on the importance of screening for and treating the individual risk factor components of MetS. Focusing attention on children with cardiometabolic risk factor clustering is emphasized over the need to define a pediatric MetS.

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Section: Defining Mets In Pediatricsmentioning

confidence: 99%

“…The instability was not related to change in weight status. 35 Thus, MetS is highly unstable throughout childhood. A child can meet the criteria at 1 point in time and not meet it at another point in time, and it is unclear whether this variation represents an improvement or deterioration in health status.…”

Section: Defining Mets In Pediatricsmentioning

confidence: 99%

The Metabolic Syndrome in Children and Adolescents: Shifting the Focus to Cardiometabolic Risk Factor Clustering

2017

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“…However, the clinical utility of the metabolic syndrome in pediatrics remains unclear (Daniels, 2009). There is also quite limited stability for the diagnosis of metabolic syndrome among children and adolescents (Goodman, Daniels, Meigs, & Dolan, 2007; Goodman et al, 2009; Gustafson et al, 2009; Stanley, Chen, & Goodman, 2014). A detailed scientific statement appraising the evidence for utility of the metabolic syndrome in pediatrics is available from the American Heart Association (Steinberger et al, 2009).…”

Section: Consequences Of Pediatric Obesitymentioning

confidence: 99%

Pediatric obesity. An introduction

Yanovski

2015

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The prevalence of child and adolescent obesity in the United States increased dramatically between 1970 and 2000, and there are few indications that the rates of childhood obesity are decreasing. Obesity is associated with myriad medical, psychological, and neurocognitive abnormalities that impact children’s health and quality of life. Genotypic variation is important in determining the susceptibility of individual children to undue gains in adiposity; however, the rapid increase in pediatric obesity prevalence suggests that changes to children’s environments and/or to their learned behaviors may dramatically affect body weight regulation. This paper presents an overview of the epidemiology, consequences, and etiopathogenesis of pediatric obesity, serving as a general introduction to the subsequent papers in this Special Issue that address aspects of childhood obesity and cognition in detail.

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“…Em pessoas jovens obesas representa um problema para saúde pública, especialmente considerando a idade pós-púbere, quando a obesidade tem um grande risco de permanecer até a idade adulta (14) . Em 10 anos, a prevalência da obesidade e da SM aumentará consideravelmente nos indivíduos em transição de faixa etária (de crianças e adolescentes para adultos jovens), de 21% para 33,4% e de 2,8% para 17,9%, respectivamente (15) . Além disso, no Brasil, o número de adolescentes do sexo masculino entre 10 a 19 anos idade com excesso de peso passou de 3,7% (1974-1975) para 21,7% (2008-2009), e o número de adolescentes do sexo feminino com excesso de peso passou de 7,6% para 19,4%, no mesmo período, segundo a Pesquisa de Orçamento Familiar (POF) (16) .…”

Section: Introductionunclassified

Esteatose hepática não alcoólica: relação com a síndrome metabólica e os fatores de risco cardiovascular em adolescentes obesos

Resende¹,

Caetano²,

Nogueira³

et al. 2014

RBPS

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A amostra foi composta de 14 indivíduos do sexo masculino e 20 do sexo feminino, com idade (16,8±1,6) e índice de massa corporal (IMC) (35,7±3,9). A ocorrência de EHNA e SM foi de 76,5% (n=26) e 50% (n=17), respectivamente. O sexo masculino apresentou maior ocorrência de EHNA (78,6%, n=11), SM (64,3%, n=09) e associação de EHNA com SM (50%, n=07). Em relação aos FRCs 100% (n=34), 61,8% (n=21) e 52,9% (n=18) dos adolescentes apresentaram valores aumentados da circunferência da cintura (CC), da lowdensity-lipoprotein cholesterol (LDL-C) e pressão arterial sistólica (PAS), respectivamente, e 52,9% (n=18) apresentaram baixos valores de high-density lipoprotein cholesterol (HDL-C). Houve correlações entre SM e triglicerídeos, PAS e diastólica e HDL-C, e entre EHNA, IMC e CC. Conclusão: Observou-se uma alta ocorrência de EHNA, SM e FRCs em adolescentes obesos. Uma forte correlação foi observada entre EHNA e SM, e entre FRCs com EHNA e SM.Descritores: Adolescentes; Obesidade Infantil; Fígado Gorduroso; Síndrome X Metabólica; Doenças Cardiovasculares. (LDL-C) ABSTRACT Objective: To evaluate the association between nonalcoholic hepatic steatosis (NAHS), metabolic syndrome (MS) and cardiovascular risk factors (CRF) in obese adolescents

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The Typology of Metabolic Syndrome in the Transition to Adulthood

Abstract: During the transition to adulthood, the diagnosis of MetS is highly unstable and fluctuates even among those who are obese and gaining weight.

Cited by 22 publications

References 40 publications

The Metabolic Syndrome in Children and Adolescents: Shifting the Focus to Cardiometabolic Risk Factor Clustering

The Metabolic Syndrome in Children and Adolescents: Shifting the Focus to Cardiometabolic Risk Factor Clustering

Pediatric obesity. An introduction

Esteatose hepática não alcoólica: relação com a síndrome metabólica e os fatores de risco cardiovascular em adolescentes obesos

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