The type II secretion system as an underappreciated and understudied mediator of interbacterial antagonism
Nicholas P. Cianciotto
Abstract:Interbacterial antagonism involves all major phyla, occurs across the full range of ecological niches, and has great significance for the environment, clinical arena, and agricultural and industrial sectors. Though the earliest insight into interbacterial antagonism traces back to the discovery of antibiotics, a paradigm shift happened when it was learned that protein secretion systems (e.g., types VI and IV secretion systems) deliver toxic “effectors” against competitors. However, a link between interbacteria… Show more
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