The tumour‐derived extracellular vesicle proteome varies by endometrial cancer histology and is confounded by an obesogenic environment
Anastasiia Artuyants,
George Guo,
Marcella Flinterman
et al.
Abstract:Endometrial cancer, the most common gynaecological cancer worldwide, is closely linked to obesity and metabolic diseases, particularly in younger women. New circulating biomarkers have the potential to improve diagnosis and treatment selections, which could significantly improve outcomes. Our approach focuses on extracellular vesicle (EV) biomarker discovery by directly profiling the proteome of EVs enriched from frozen biobanked endometrial tumours. We analysed nine tissue samples to compare three clinical su… Show more
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