The Tumor Growth Inhibitory Effect of a Standardized Extract of Cultured <i>Lentinula edodes</i> Mycelia Using Patient Derived Xenograft Model
Remi Yoshii,
Shigeki Adachi,
Haruko Ryo
et al.
Abstract:Patient derived xenograft (PDX) is a powerful tool to confirm pharmacological efficacy in non-clinical studies for the development of various drugs including anti-cancer agents and therapeutic research. A standardized extract of cultured Lentinula edodes mycelia, a product name AHCC ® is produced by Amino Up Co., Ltd. (Sapporo, Japan). In this study, we investigated the inhibitory effect of AHCC ® on the growth of tumor PDX in Super SCID (severe combined immunodeficiency) mice. Effects of AHCC ® and BCG admini… Show more
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