The True Incidence of Cryptorchidism in Denmark

Cortes, Dina; Kjellberg, Emma; Breddam, Mette; Thorup, Jørgen

doi:10.1016/j.juro.2007.08.158

Cited by 87 publications

(69 citation statements)

References 19 publications

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“…However the report by Cortes (2008) has shown that the incidence of cryptorchidism in Denmark has not changed and is similar to the previous reports obtained in the 1950s. They have pointed out the general difficulties to compare the frequency of cryptorchidism as reported in different publications, since the definition of cryptorchidism is not yet uniform (Cortes 2008). The International Clearinghouse for Birth Defects Monitoring System has collected data on cryptorchidism, but they are unreliable, because of a discrepancy with the data from cohort studies (Toppari 2001).…”

Section: Introductionsupporting

confidence: 87%

“…(Toppari 2001). However the report by Cortes (2008) has shown that the incidence of cryptorchidism in Denmark has not changed and is similar to the previous reports obtained in the 1950s. They have pointed out the general difficulties to compare the frequency of cryptorchidism as reported in different publications, since the definition of cryptorchidism is not yet uniform (Cortes 2008).…”

Section: Introductionsupporting

confidence: 84%

See 1 more Smart Citation

Cryptorchidism and Steroid Hormones

Kamieniczna¹,

Havrylyuk²,

Kurpisz³

2012

Steroids - Basic Science

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Section: Introductionsupporting

confidence: 87%

Section: Introductionsupporting

confidence: 84%

Cryptorchidism and Steroid Hormones

Kamieniczna¹,

Havrylyuk²,

Kurpisz³

2012

Steroids - Basic Science

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“…Cryptorchidism affects between 2·4 and 5 per cent of live‐born boys1, 2, 3, 4. Undescended testes are known to be associated with an increased incidence of testicular malignancy and subfertility, even after orchidopexy5, 6, 7, 8, 9, 10.…”

Section: Introductionmentioning

confidence: 99%

Systematic review and meta-analysis comparing outcomes following orchidopexy for cryptorchidism before or after 1 year of age

et al. 2018

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BackgroundCurrent guidelines recommend orchidopexy for cryptorchidism by 12 months of age, yet this is not universally adhered to. The aim of this systematic review and meta‐analysis was to compare outcomes between orchidopexies performed before and after 1 year of age.MethodsMEDLINE and Embase were searched (September 2015) using terms relating to cryptorchidism, orchidopexy and the outcomes of interest. Studies were eligible for inclusion if they compared orchidopexy at less than 1 year of age (early) with orchidopexy at 1 year or more of age (delayed) and reported the primary outcome (testicular atrophy) or one of the secondary outcomes (fertility potential, postoperative complication, malignancy). Studies were excluded when more than 50 per cent of infants had intra‐abdominal testes, or the population included infants with disorders of sexual differentiation. Additional studies were identified through reference list searching. Unpublished data were sought from the ORCHESTRA study investigators.ResultsFifteen eligible studies were identified from 1387 titles. There was no difference in atrophy rate between early orchidopexy and delayed orchidopexy (risk ratio 0·64, 95 per cent c.i. 0·25 to 1·66; 912 testes). Testicular volume was greater (mean difference 0·06 (95 per cent c.i. 0·01 to 0·10) ml; 346 testes) and there were more spermatogonia per tubule (mean difference 0·47 (0·31 to 0·64); 382 testes) in infants undergoing early orchidopexy, with no difference in complication rate (risk ratio 0·68, 0·27 to 1·68; 426 testes). No study reported malignancy rate.ConclusionAtrophy and complication rates do not appear different between early and delayed orchidopexy, and fertility potential may be better with early orchidopexy. Imprecision of the available data limits the robustness of these conclusions.

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“…Their search "hypospadias OR cryptorchidism OR testicular dysgenesis" yielded 15,639 articles. Combination of the two sets, they found, produced 188 papers, but, they pointed out, the "notable papers" by Thorup et al (2010) and Cortes et al (2008) were not among them. However, we cited the paper by Cortes et al (2008).…”

mentioning

confidence: 99%

“…Combination of the two sets, they found, produced 188 papers, but, they pointed out, the "notable papers" by Thorup et al (2010) and Cortes et al (2008) were not among them. However, we cited the paper by Cortes et al (2008). Astonishingly, the authors accuse us of bias because we did not mention Thorup et al (2010).…”

mentioning

confidence: 99%