2005
DOI: 10.1055/s-2005-870130
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The Treatment of Patients with Symptomatic Common Bile Duct Stenosis Secondary to Chronic Pancreatitis Using Partially Covered Metal Stents: A Pilot Study

Abstract: While partially covered metal stenting is safe and effective for the initial treatment of chronic pancreatitis-associated common bile duct stenosis and shows promising short-term results, long-term data show that dysfunction occurs in 50 % of cases. In light of the continued interest in nonsurgical treatment of this condition, further research is warranted to investigate new stent designs with improved long-term patency.

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Cited by 79 publications
(54 citation statements)
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“…12 Biliary metal stents have recently been used to maintain ductal patency in patients with benign biliary strictures. [13][14][15] However, the use of an uncovered SEMS for benign biliary strictures is highly controversial because they are associated with epithelial hyperplasia, leading to chronic inflammation and becoming embedded in the bile duct wall. 15,16 Temporary placement of covered SEMSs for benign biliary strictures may offer an alternative to plastic stenting, but is associated with migration.…”
Section: Discussionmentioning
confidence: 99%
“…12 Biliary metal stents have recently been used to maintain ductal patency in patients with benign biliary strictures. [13][14][15] However, the use of an uncovered SEMS for benign biliary strictures is highly controversial because they are associated with epithelial hyperplasia, leading to chronic inflammation and becoming embedded in the bile duct wall. 15,16 Temporary placement of covered SEMSs for benign biliary strictures may offer an alternative to plastic stenting, but is associated with migration.…”
Section: Discussionmentioning
confidence: 99%
“…More aggressive endoscopic therapy, by placement of multiple plastic stents, can obtain stricture resolution in 44−90% of cases with a 13-48 months follow-up period after stent removal [208][209][210]. Although the role of self-expandable metal stents is well established for malignant obstruction, their use in benign strictures including chronic pancreatitis is less clear and controversial [211][212][213]. Clogging or dysfunction of these stents is reported in 10−62% of the cases after a mean follow-up of 22-50 months.…”
Section: E3: Is Endoscopic Therapy Indicated In Chronic Pancreatitismentioning
confidence: 99%
“…This capacity, combined with the larger diameter of the covered metal stent makes stepwise dilation, as is performed with multiple plastic stents, unnecessary and may thus reduce the number of procedures (24). The clinical experience with covered metal stents for benign biliary strictures has until now been only limited (24,25). Covered metal stent placement for benign biliary strictures is still associated with relatively high complication rates (39.6%).…”
Section: Discussionmentioning
confidence: 99%