The Treatment of Carcinoma of the Prostate by Interstitial Radiation with Radioactive Gold (Au
            <sup>198</sup>
            ): A Follow-Up Report

Flocks, R.H.; Kerr, H. Dabney; Elkins, H.B.; Culp, David A.

doi:10.1016/s0022-5347(17)67835-2

Cited by 49 publications

(11 citation statements)

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“…(2) Patients can stay in a normal ward, except for irradiation time of around 10-30 min per day. (3) No radioactivity or material is left in the body of the patient after treatment. (4) The HDR source can reach outside the prostate capsule, even into the seminal vesicle and the bladder pouch, because the source just goes into the closed-end needles and comes back.…”

Section: Permanent Implant Brachytherapy (Pib)mentioning

confidence: 99%

Current status and perspectives of brachytherapy for prostate cancer

Yoshioka

2009

Int J Clin Oncol

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Permanent implant brachytherapy (PIB) for prostate cancer in a modern style was introduced in the 1980s. With the excellent outcome, the method prevailed rapidly in the United States in the 1990s, and it has become a standard treatment option at least for low-risk prostate cancer today. In Japan, PIB using (125)I free seeds was started in 2003, and it is being rapidly accepted. About 90 institutions in Japan have already started PIB, and about 10 000 patients have received this treatment during these 5 years. The outcome data for Japanese men should be established, and the efficacy of the combined use of external beam radiation therapy (EBRT) and hormone therapy should be examined. High-dose-rate (HDR) brachytherapy, which has many advantages over PIB, was started in the 1980s, firstly as a boost combined with EBRT, in Europe and the United States. In Japan, combined HDR brachytherapy and EBRT therapy was started in 1994. As for monotherapeutic HDR brachytherapy, the first series in the world was initiated in Osaka, Japan, in 1995. HDR brachytherapy, both as monotherapy and as combined therapy with EBRT, is yielding promising outcomes, and the study of these modalities should be continued. Mutual understanding and cooperation among urologists, radiation oncologists, and medical physicists is essential to enhance brachytherapy for prostate cancer.

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Section: Permanent Implant Brachytherapy (Pib)mentioning

confidence: 99%

Current status and perspectives of brachytherapy for prostate cancer

Yoshioka

2009

Int J Clin Oncol

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“…In 1952, Flocks et al [18] renewed the interest in brachytherapy by introducing the transvesical approach for gold 198 implantation.…”

Section: Brachytherapymentioning

confidence: 99%

Alternative therapies for localized prostate cancer

Beerlage

2003

Curr prostate rep

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“…In 1952, interest was renewed in radiation therapy of prostatic cancer when Flocks et al introduced interstitial injection of colloidal solution of radioactive gold into the prostata during open operations [5]. Since then, an increas-ing experience with various forms of interstitial and/or external irradiation has accumulated.…”

Section: Early Interstitial Implants In the Prostatementioning

confidence: 99%

The history of interstitial brachytherapy of prostatic cancer

Holm

1997

Semin. Surg. Oncol.

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The history of interstitial brachytherapy of the prostate began in 1917 when Barringer inserted radium needles transperineally into the prostate, guided by a finger in the rectum. In 1952, Flocks et al. Injected radioactive gold solution in prostatic cancer during open operation. In 1972, Whitmore et al. Described retropubic Iodine‐125 seed implantation through an open operation with pelvic lymph node dissection. The basis for ultrasound (US)‐guided seed implantation was established in the late 1960s by Kratochwil's description of the first puncture transducer for one‐dimensional US‐guidance and Watanabe's pioneer work in prostatic screening. Our group performed the first punctures guided by static two‐dimensional ultrasonic scanning (1969) and by dynamic ultrasound scanning (1974). During the 1970s, US‐guided biopsies of almost all abdominal organs were performed and, in 1981, we introduced US‐guided seed implantation of abdominal tumors and developed a technique for precise needle placement in the prostate guided by transrectal ultrasound. This was followed in 1983 by a technique for seed implantation guided by transrectal (transverse) ultrasonic scanning. That same year, Fornage described prostatic biopsy guided by transrectal longitudinal scanning. In 1990, we developed the seed implantation technique further by combining transverse and longitudinal scannings. In the late 1980s, Ragde from Seattle transferred the technique to the U.S., and since then, Ragde, Blasko, and others have treated numerous patients, refined the technique, taught many courses, and published extensively. They have obtained very promising prostate‐specific antigen (PSA)‐based results which compare favorably with radical prostatectomy and external beam radiation in the treatment of prostatic cancer. Semin. Surg. Oncol. 13:431‐437, 1997. © 1997 Wiley‐Liss, Inc.

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The Treatment of Carcinoma of the Prostate by Interstitial Radiation with Radioactive Gold (Au ¹⁹⁸ ): A Follow-Up Report

Cited by 49 publications

References 1 publication

Current status and perspectives of brachytherapy for prostate cancer

Current status and perspectives of brachytherapy for prostate cancer

Alternative therapies for localized prostate cancer

The history of interstitial brachytherapy of prostatic cancer

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The Treatment of Carcinoma of the Prostate by Interstitial Radiation with Radioactive Gold (Au 198 ): A Follow-Up Report

Cited by 49 publications

References 1 publication

Current status and perspectives of brachytherapy for prostate cancer

Current status and perspectives of brachytherapy for prostate cancer

Alternative therapies for localized prostate cancer

The history of interstitial brachytherapy of prostatic cancer

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Product

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About

The Treatment of Carcinoma of the Prostate by Interstitial Radiation with Radioactive Gold (Au ¹⁹⁸ ): A Follow-Up Report