The Treatment of Carcinoma of the Esophagus and Cardia by Resection and Postoperative Supervoltage Roentgen Rays

Adams, Herbert D.; Hare, Hugh F.; Davis, Wirt L.; Trump, John G.; Granke, Richard C.

doi:10.1097/00000658-195310000-00016

Cited by 14 publications

(5 citation statements)

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“…There has been only one paper, case reports by Adams in [74], on postoperative radiotherapy; he did not, however, discuss prognosis. Based on our previous experience with poor prognosis in patients treated with preoperative radiotherapy (a high dose for a short period), postoperative radiotherapy was systematically started at our institution in 1970.…”

Section: Postoperative Radiotherapymentioning

confidence: 99%

Adjuvant therapies for cancer of the thoracic esophagus

1994

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During the past four decades, especially in recent years, various active adjuvant therapies combined with surgery have improved the outcome in cases of cancer of the esophagus. However, no optimum adjuvant therapy has been determined. From 1981 to 1992, 341 patients with regional and distant node metastasis who underwent curative surgery were treated with postoperative radiotherapy (RT), postoperative radiochemotherapy (RC), and postoperative aggressive chemotherapy (AGC) in a controlled study in our department of surgery. Five-year survival rates, including operative deaths and unrelated diseases of the former group, were 0% for RT, 19.9% for surgery alone, 39.8% for RC, and 48.2% for AGC. Such rates for the latter group were 6.8% for AGC, 13.3% for surgery alone, and 33.3% for RC. In addition, results of a group study on the effectiveness of three-field node dissection in 715 cases of thoracic esophageal carcinoma by 10 institutions were analyzed. This analysis showed that there were no differences in the 5-year survival rate of curative surgery in cases with positive nodes among the groups treated with surgery alone (SA), with postoperative radiotherapy (PR), and with postoperative chemotherapy (PC). As to the 91 cases with positive cervical nodes, the 3-year survival rates in cases treated with SA (n = 22), PR (n = 20), and PC (n = 49) were 25.3%, 48.1%, and 53.6%, respectively; a significant improvement of survival in these patients. Summaries of studies of preoperative or postoperative radiotherapy, and both multimodal therapies are introduced.

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Section: Postoperative Radiotherapymentioning

confidence: 99%

Adjuvant therapies for cancer of the thoracic esophagus

1994

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“…The stenotic stoma of the previously carried out anastomosis was excised and stomach and esophagus reanastomosed. Three months later the patient had gained 35 \s=s\SeeAddendum. Alive and well 10 months later, this patient has survived the five-year period.…”

Section: Carcinoma Of the Cardiamentioning

confidence: 99%

“…This combined with supervoltage roentgen ray therapy of the residual tumor might well be of some benefit. Adams and his associates 35 have mentioned such postoperative roentgen ray therapy, and their results will be of great interest. SUMMARY A summary of a small group of 54 patients with carcinoma of the esophagus and the cardia has been undertaken, and the results in terms of months of palliation achieved by operative procedures are submitted.…”

Section: Effect Of Metastasesmentioning

confidence: 99%

Results of Surgical Treatment of Carcinoma of the Esophagus and Gastric Cardia

Chauncey¹

1954

AMA Arch Surg

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“…Administration of a tumor dose of approximately 6,000 rads results in palliation for a large percentage of patients. 1 Since such a high percentage of patients show temporary marked improvement in swallowing, as shown by the esophagram, and in general well-being, it seemed logical to under- take a study of preoperative radiation followed by surgical excision. In our own experience, radiation therapy has resulted in significant palliation in approximately 60% of patients.…”

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confidence: 99%

“…16 Postoperative radiation therapy has also been used. 1 Since such a high percentage of patients show temporary marked improvement in swallowing, as shown by the esophagram, and in general well-being, it seemed logical to under- take a study of preoperative radiation followed by surgical excision. Previous experience in other institutions, which included a reported case of a patient who survived more than 3 years after preoperative irradiation and esophagectomy for a previously inoperable lesion,6 was the background for this plan.…”

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confidence: 99%