“…When stratifying centers by rates of TRA adoption, however, the decline in bleeding outcomes was significantly larger at hospitals with more rapid adoption of TRA than with those with little or no change in TRA utilization. 25 Superior outcomes, including lower rates of bleeding and at times improved in-hospital mortality, have been widely reported for TRA than for TFA in primary PCI for STEMI and include multiple randomized trials, 4,11,13 several recent meta-analyses, 12,[26][27][28] and a large volume of observational data. 1,14,29,30 The majority of randomized data showing clinical benefit from TRA PCI have been from high-volume, experienced providers.…”