The Transport and Deposition of Nanoparticles in Respiratory System by Inhalation

Qiao, Huiting; Liu, Wenyong; Gu, Hengfei; Wang, Daifa; Wang, Yu

doi:10.1155/2015/394507

Cited by 58 publications

(37 citation statements)

References 103 publications

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“…The release of AgNPs in the environment during the manufacturing, washing or disposal of products enables the NPs to enter the human respiratory system through inhalation [82]. An exposure assessment in an NMs manufacturing facility showed a significant release of AgNPs during processing as soon as the reactor, dryer and grinder were opened, leading to potential occupational exposure even for wet production processes [83].…”

Section: Respiratory Exposurementioning

confidence: 99%

Health Impact of Silver Nanoparticles: A Review of the Biodistribution and Toxicity Following Various Routes of Exposure

Ferdous

Nemmar

2020

IJMS

640

354

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Engineered nanomaterials (ENMs) have gained huge importance in technological advancements over the past few years. Among the various ENMs, silver nanoparticles (AgNPs) have become one of the most explored nanotechnology-derived nanostructures and have been intensively investigated for their unique physicochemical properties. The widespread commercial and biomedical application of nanosilver include its use as a catalyst and an optical receptor in cosmetics, electronics and textile engineering, as a bactericidal agent, and in wound dressings, surgical instruments, and disinfectants. This, in turn, has increased the potential for interactions of AgNPs with terrestrial and aquatic environments, as well as potential exposure and toxicity to human health. In the present review, after giving an overview of ENMs, we discuss the current advances on the physiochemical properties of AgNPs with specific emphasis on biodistribution and both in vitro and in vivo toxicity following various routes of exposure. Most in vitro studies have demonstrated the size-, dose- and coating-dependent cellular uptake of AgNPs. Following NPs exposure, in vivo biodistribution studies have reported Ag accumulation and toxicity to local as well as distant organs. Though there has been an increase in the number of studies in this area, more investigations are required to understand the mechanisms of toxicity following various modes of exposure to AgNPs.

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Section: Respiratory Exposurementioning

confidence: 99%

Health Impact of Silver Nanoparticles: A Review of the Biodistribution and Toxicity Following Various Routes of Exposure

Ferdous

Nemmar

2020

IJMS

640

354

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“…The size of nanoparticles is a very important feature for its unique properties as the surface area of nanoparticles depends upon its size. The effect of surface area on the respiration has been known as some nanoparticles are reported to cause pulmonary inflammation (Qiao et al 2015). The toxicity of these nanoparticles not only depends on its chemical component, but it also depends on the quantity as well as position of the deposition.…”

Section: Sizementioning

confidence: 99%

Use of Nanomaterials in Food Science

Ameta

Kumar²,

Hiran³

et al. 2020

Biogenic Nano-Particles and Their Use in Agro-Ecosystems

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The current global population is nearly 6 billion; due to this rapid population growth, there is a need to produce food in a more efficient, safe, and sustainable way, and it should be safe from the adverse effects of pathogenic organisms. A large proportion of population living in developing countries face daily food shortages as a result of environmental impacts or some other reasons like political instability, etc., while in the developed countries, food is surplus. For developing countries, the objective is to develop drought-and pest-resistant crops, with maximized yield. In developed countries, the food industry depends on consumer's demand for fresher and healthier foodstuffs. The present chapter describes the use of nanoparticles in food science.

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“…Nanoparticles in the air easily enter the respiratory system [84]. These particles come largely from industrial processes, and can pose a threat to people in contact with them [85].…”

Section: Uncontrolled Exposure To Nanoparticlesmentioning

confidence: 99%

Analysis of the Exposure of Organisms to the Action of Nanomaterials

et al. 2020

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The rapid development of the production of materials containing metal nanoparticles and metal oxides is a potential risk to the environment. The degree of exposure of organisms to nanoparticles increases from year to year, and its effects are not fully known. This is due to the fact that the range of nanoparticle interactions on cells, tissues and the environment requires careful analysis. It is necessary to develop methods for testing the properties of nanomaterials and the mechanisms of their impact on individual cells as well as on entire organisms. The particular need to raise public awareness of the main sources of exposure to nanoparticles should also be highlighted. This paper presents the main sources and possible routes of exposure to metal nanoparticles and metal oxides. Key elements of research on the impact of nanoparticles on organisms, that is, in vitro tests, in vivo tests and methods of detection of nanoparticles in organisms, are presented.

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The Transport and Deposition of Nanoparticles in Respiratory System by Inhalation

Cited by 58 publications

References 103 publications

Health Impact of Silver Nanoparticles: A Review of the Biodistribution and Toxicity Following Various Routes of Exposure

Health Impact of Silver Nanoparticles: A Review of the Biodistribution and Toxicity Following Various Routes of Exposure

Use of Nanomaterials in Food Science

Analysis of the Exposure of Organisms to the Action of Nanomaterials

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