The translational paradigm of nanobiomaterials: Biological chemistry to modern applications

Sinha, Adrija; Simnani, Faizan Zarreen; Singh, Dibyangshee; Nandi, Aditya; Choudhury, Anmol; Patel, Paritosh; Jha, Ealisha; Chouhan, Raghuraj Singh; Kaushik, Nagendra Kumar; Mishra, Yogendra Kumar; Panda, Pritam Kumar; Suar, Mrutyunjay; Verma, Suresh K.

doi:10.1016/j.mtbio.2022.100463

Cited by 20 publications

(4 citation statements)

References 253 publications

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“…Understanding potential toxicological effects after exposure require the characterization of nanoparticles and nanogels. Nanoparticles and nano-gels must be characterized using proper analytical methods to determine their size, shape, surface area, morphology, and charge 16 , 18 , 20 . We used FTIR, XRD, ZETA-Sizer, EDAX analysis, FE-SEM, and TEM to characterize the herbal-based nanogel of Mattan tailam .…”

Section: Discussionmentioning

confidence: 99%

“…The new drug carrier should have two main features: delivering the drug at the required rate and effectively delivering the drug to the site of action. Therefore, nanogels have many advanced functions, which can be equivalent to the demand for modern medicines 18 , 19 . Nanogels are used for local and systemic drugs due to their inherent swelling properties, which are attributed to their chemical modification to help release the drug in the desired dosage form 20 .…”

Section: Introductionmentioning

confidence: 99%

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Formulation, Characterization, and Evaluation of Wound Healing Potency of a Novel Mattan tailam Nanogel Based on a Famous Traditional Siddha Formula

Sakthiganapathi¹,

Yoganandam²,

Gopal³

2022

AJMB

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Background: The Mattan tailam mixture has been extensively used to heal ulcerous wounds in traditional Siddha practice. The present study aimed to synthesize a Mattan tailam nanogel and evaluate the enhancement of wound healing potential in an experimental wound model. Methods: Mattan tailam nanogel was synthesized using the high-energy milling approach, and characterization of nanogel and potency of wound healing was investigated. The novelty of this study was the nanogel preparation of Mattan tailam. Results: As expected, a synthesized novel nanogel of Mattan tailam has a distinct, prominent peak with a spherical form, is negatively charged and has an average particle size of 20–30 nm. Mattan tailam nanogel treated rats showed a remarkable reduction (p<0.001) in the wound area. On the 16th day, 10% Mattan tailam nanogel treatment resulted in a higher percentage of wound contraction. The 10% Mattan tailam nanogel group exhibited a faster epithelialization time (14.33 days) and a greater hydroxyproline concentration than the others. The topical application of 10% Mattan tailam nanogel increased tensile strength, signifying a better therapeutic indication. Conclusion: The present findings prove that polyherbal Mattan tailam nanogel formulation significantly improves collagen production, wound contraction, and tensile strength.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Formulation, Characterization, and Evaluation of Wound Healing Potency of a Novel Mattan tailam Nanogel Based on a Famous Traditional Siddha Formula

Sakthiganapathi¹,

Yoganandam²,

Gopal³

2022

AJMB

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“…Furthermore, hybrid nanosystems, functionalized with nano/xeno bots, nanorobots can change the fate of future medicines with their prospective application in internal damage repair, artery scraping and sophisticated drug delivery. 224 Along with these hybrids system future advanced nanostructured materials will facilitate high porosity, numerous active sites, large surface area, enhanced catalytic activity, and modular structure, and are ideal for sensing and catalytic applications. The outlook about potential pathways to utilize fNPs in precision engineering applications is listed in Table 7.…”

Section: Outlook and Prospectsmentioning

confidence: 99%

Functionalized nanoparticles: Tailoring properties through surface energetics and coordination chemistry for advanced biomedical applications

et al. 2023

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“…The electronic structure of these P-type amorphous silicon nanowires is attracting the attention of researchers worldwide because of their potential to provide revolutionary solutions in various fields [3], including nanoelectronics and photovoltaics [4]. The rapid growth in the development of nanomaterial technology has fundamentally changed the paradigm of scientific and industrial research [5]. Nanomaterials, which are measured on the nanometre scale, offer unique properties and characteristics, enabling the creation of materials with outstanding performance and functionality [6].…”

Section: Introductionmentioning

confidence: 99%

Electronic structure of P-type amorphous silicon nanowires

Prayogi,

Kresna,

Cahyono

et al. 2023

Phys. Scr.

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Silicon nanowires can improve broadband optical absorption and reduce the radial carrier collection distance in solar cell devices. The disordered nanowire arrays grown by the Plasma-Enhanced Chemical Vapor Deposition method are attractive because they can be embedded on low-cost substrates such as glass, and are compatible with large areas. Here, we experimentally demonstrate that reactive Hydrogen ions with increasing concentrations are doped to construct nanowire architectures in amorphous silicon solar cells. Similar to our investigated planar a-Si: H layers, the amorphous silicon nanowires exhibit a loss function coefficient of about 105/cm. From the reflectivity function, it can be shown that the nanostructures can offer a reliable carrier pool. Our results show that the addition of nanowires can increase the efficiency of a-Si solar cells from 1.11% to 1.57%. The input-photon-to-current conversion efficiency spectrum shows effective carrier collection from 1.2 to 2.2 eV of incident light and the nanowire devices show an increase in short-circuit current of 15% with amorphous Si and 26% with nanocrystalline Si compared to planar devices appropriate.

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The translational paradigm of nanobiomaterials: Biological chemistry to modern applications

Cited by 20 publications

References 253 publications

Formulation, Characterization, and Evaluation of Wound Healing Potency of a Novel Mattan tailam Nanogel Based on a Famous Traditional Siddha Formula

Formulation, Characterization, and Evaluation of Wound Healing Potency of a Novel Mattan tailam Nanogel Based on a Famous Traditional Siddha Formula

Functionalized nanoparticles: Tailoring properties through surface energetics and coordination chemistry for advanced biomedical applications

Electronic structure of P-type amorphous silicon nanowires

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