The transition to young adulthood in youth with type 1 diabetes on intensive treatment

Insabella, Glendessa M.; Grey, Margaret; Knafl, George J.; Tamborlane, William V.

doi:10.1111/j.1399-5448.2007.00266.x

Cited by 85 publications

(90 citation statements)

References 27 publications

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“…For instance, a prospective study that aimed to assess the impact on the QoL over 5 years in a cohort of 117 diabetic patients showed that despite the damage on metabolic control, the QoL did not change over time. 27 The reasons for the improvement of HbA1c and absence of HRQoL remain open for discussion. Organization of care, stricter guidelines, more education, length of follow-up, a more active role of children and adolescents themselves, and the socioeconomic level of their parents may be involved.…”

Section: Discussionmentioning

confidence: 99%

The effect of free diabetes care on metabolic control and on health-related quality of life among youths with type 1 diabetes in Cameroon

Lontchi-Yimagou

Mapa-Tassou

Dehayem

et al. 2017

BMJ Open Diab Res Care

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ObjectiveTo assess the effect of free diabetes care on metabolic control and on health-related quality of life (HRQoL) of youths living with type 1 diabetes in Cameroon.Research design and methodsWe conducted a clinical audit of a multicenter prospective cohort, performed in three of the nine clinics of the ‘Changing Diabetes in Children’ (CDiC) project in Cameroon. We collected data on demography, glycemic control, diabetes acute complications, and patients’ HRQoL at baseline and after 1 year of follow-up.ResultsOne hundred and four patients (51 female) were included. The mean age was 16±2 years (min–max: 9–18), the mean duration of diabetes was 5±3 years, and the mean HbA1C level was 11.4%±2.7%. A significant reduction in HbA1c (11.4%±2.7% vs 8.7±2.4%), episodes of severe hypoglycemia (27/104 vs 15/104), and episodes of ketoacidosis (31/104 vs 7/104) were observed after 1 year (p<0.05). We did not observe any significant difference in the total HRQoL score (p=0.66). However, we observed a significant decrease in diabetes-associated symptoms (p<0.05). Age, level of education, duration of diabetes, glycemic control, and the presence or absence of diabetes complications did not significantly affect the total HRQoL score.ConclusionsOne year after free diabetes care offered through the CDiC project, a significant improvement was observed in glycemic control and acute complications of diabetes, but not in the total score of HRQoL of youths living with type 1 diabetes enrolled in the project.

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Section: Discussionmentioning

confidence: 99%

The effect of free diabetes care on metabolic control and on health-related quality of life among youths with type 1 diabetes in Cameroon

Lontchi-Yimagou

Mapa-Tassou

Dehayem

et al. 2017

BMJ Open Diab Res Care

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“…Therefore, one may speculate whether implementation of CGM from the onset of clinical disease may have an especially positive effect in the adolescent patient cohort independent of glycaemic control as seen in the present study. Moreover, imperfect adherence with long-term diabetes management has been recognised as a limitation to achieve good metabolic control in adolescents and young adults [15][16][17]. Taken together, the rapid introduction of continuous glucose monitoring into diabetes treatment may be helpful and effective from both metabolic and educational aspects.…”

Section: Discussionmentioning

confidence: 99%

Sensor-augmented pump therapy from the diagnosis of childhood type 1 diabetes: results of the Paediatric Onset Study (ONSET) after 12 months of treatment

et al. 2010

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Aims/hypothesis The value of managing children with type 1 diabetes using a combination of insulin pump and continuous glucose monitoring starting from diagnosis for improving subsequent glycaemic control and preserving residual beta cell function was determined. Methods A total of 160 children (aged 1-16 years, mean± SD: 8.7±4.4 years; 47.5% girls) were randomised to receive insulin pump treatment with continuous glucose monitoring or conventional self-monitoring blood glucose measurements. The primary outcome was the level of HbA 1c after 12 months. Other analyses included fasting C-peptide, glycaemic variability, sensor usage, adverse events, children's health-related quality of life and parent's wellbeing. Results HbA 1c was not significantly different between the two groups, but patients with regular sensor use had lower values (mean 7.1%, 95% CI 6.8-7.4%) compared with the combined group with no or low sensor usage (mean 7.6%, 95% CI 7.3-7.9%; p=0.032). At 12 months, glycaemic variability was lower in the sensor group (mean amplitude of glycaemic excursions 80.2 ± 26.2 vs 92.0 ± 33.7; p=0.037). Higher C-peptide concentrations were seen in sensor-treated 12-to 16-year-old patients (0.25±0.12 nmol/l) Electronic supplementary material The online version of this article

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“…Despite the harm caused for metabolic control, QoL did not change over time, at a 95% confidence interval (22) .…”

Section: Qol and Socio-demographic Factorsmentioning

confidence: 99%

Fatores associados à qualidade de vida de jovens com diabetes mellitus do tipo 1

Novato

Grossi

2011

Rev. esc. enferm. USP

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The objective of this study was to perform a literature review of the factors that may influence the Health Related Quality of Life (HRQL) of adolescents with type 1 diabetes mellitus using the PICO strategy. PubMed/ MEDLINE, ISI Web of Knowledge and EMBASE were the databases used. A larger survey of articles was possible by combining standardized and non-standardized descriptors. Though HRQL is a specific construct used to evaluate aspects related to the repercussions of health, illness, and treatment, it appears that sociodemographic, psychosocial, and family-related aspects have a significant effect on HRQL.

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The transition to young adulthood in youth with type 1 diabetes on intensive treatment

Abstract: These data suggest that youth who begin intensive treatment as adolescents generally have good metabolic and psychosocial outcomes as young adults. However, those who have high levels of depressive symptoms in adolescence tend to continue to have such symptoms in early adulthood.

Cited by 85 publications

References 27 publications

The effect of free diabetes care on metabolic control and on health-related quality of life among youths with type 1 diabetes in Cameroon

The effect of free diabetes care on metabolic control and on health-related quality of life among youths with type 1 diabetes in Cameroon

Sensor-augmented pump therapy from the diagnosis of childhood type 1 diabetes: results of the Paediatric Onset Study (ONSET) after 12 months of treatment

Fatores associados à qualidade de vida de jovens com diabetes mellitus do tipo 1

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