2021
DOI: 10.3389/fphar.2021.652926
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The Traditional Uses, Phytochemistry and Pharmacology of Sarcandra glabra (Thunb.) Nakai, a Chinese Herb With Potential for Development: Review

Abstract: Sarcandra glabra (Thunb.) Nakai is a folk medicine with a long history in China, which has been applied to treat sore throat, abscess, even tumor and so on. Meanwhile, it is also used as tea in some areas. At present, more than 200 chemical compounds have been isolated and identified from it, such as, sesquiterpenes, flavonoids, phenolic acids, coumarins and so on. Pharmacological studies have already confirmed that the extracts of S. glabra have many effects, such as antibacterial, antiviral, anti-inflammator… Show more

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Cited by 18 publications
(24 citation statements)
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“…Herbs have a long history of prescription use in China and have become a source of drug development for many diseases. [10][11][12][13][14][15] Aspirin, the most frequently used antiplatelet agent in the clinic, is extracted from willow bark and can irreversibly inhibit the COX-1 enzyme in the AA pathway. 16 The development of novel antiplatelet therapy from herbs may be a solution to the current concerns facing antiplatelet therapy.…”
Section: Introductionmentioning
confidence: 99%
“…Herbs have a long history of prescription use in China and have become a source of drug development for many diseases. [10][11][12][13][14][15] Aspirin, the most frequently used antiplatelet agent in the clinic, is extracted from willow bark and can irreversibly inhibit the COX-1 enzyme in the AA pathway. 16 The development of novel antiplatelet therapy from herbs may be a solution to the current concerns facing antiplatelet therapy.…”
Section: Introductionmentioning
confidence: 99%
“…Among them, Honghua and Yuxingcao are well-known plants that are widely used as herbs as well as food. 33–37 FFZJF has shown to be effective in terms of treating CP. 11 More importantly, the application of FFZJF avoids the overuse of antibiotics in treating this chronic condition.…”
Section: Discussionmentioning
confidence: 99%
“…Nakai ( SG , “Jiu Jie Cha”in Chinese) has been used as an “antipyretic-detoxicate drugs” in traditional Chinese Medicine since the Qing Dynasty (AD) [ 6 ]. In the southeast region of the Guizhou province, China, ethnic people usually mix S. glabra with glutinous rice, peanuts, or soybeans as tea in daily life, as it is capable of reducing fever [ 7 ]. The State Food and Drug Administration of China has approved six SG water extract based single-drug prescriptions (Zhongjiefeng Injection, Zhongjiefeng Granules, Zhongjiefeng Tablets, XueKang Oral Liquid, XueKang Granules and Qingren Xiaoyanning Capsules) to treat upper respiratory tract infections, pneumonia, gastritis, viral myocarditis, tumor, and thrombocytopenia [ 8 ].…”
Section: Introductionmentioning
confidence: 99%
“…It was reported that SG extracts could reduce the incidence rate and mortality of restraint stress mice caused by the H 1 N 1 influenza virus [ 9 ]. More than two hundred compounds have been isolated and identified from SG extracts, including flavonoid type (astilbin), coumarin type (isofraxidin), phenolic acid type (rosmarinic acid and chlorogenic acid), and sesquiterpenes type (chloranthalactone) molecules [ 7 ]. In recent years, isofraxidin and rosmarinic acid-4- O - β - d -glucoside were found to induce anti-influenza effects [ 9 , 10 ].…”
Section: Introductionmentioning
confidence: 99%