The Toxicology Data Bank

Oxman, Michael A.; Kissman, Henry M.; Burnside, John M; Edge, Jerry R.; Haberman, Carol B.; Wykes, Arthur A.

doi:10.1021/ci60005a006

Cited by 10 publications

(3 citation statements)

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“…This project has been described in several papers. [29][30][31] The Registry of Toxic Effects of Chemical Substances (RTECS) is a compilation which provides brief descriptions of substances for which acute or other toxic effects have been reported in the literature. RTECS also provides nomenclature, CAS Registry Numbers, and some mutagenic, teratogenic, and carcinogenic effects data, as well as references to government regulations and standards.…”

Section: Early Historymentioning

confidence: 99%

Toxicology information systems: a historical perspective

Kissman¹,

Wexler²

1985

J. Chem. Inf. Comput. Sci.

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Toxicology information systems have evolved swiftly from early, library-based bibliographic tools to advanced packages utilizing sophisticated computer and telecommunication technologies. These systems have evolved concurrently with the rapid expansion of the science of toxicology itself. Bibliographic files such as TOXLINE represent first attempts to handle the toxicology literature through on-line retrieval. Subsequent approaches applied the use of computers to provide literature-derived data, as in TDB or RTECS, or to capture data directly in the laboratory. Societal concerns about hazardous substances, manifested in legislation and regulations, have been responsible for the creation of many computerized systems. Advanced, integrated information management systems are being explored as a method of accessing a large number of independently maintained toxicology databases. Changes in information technologies such as the trend toward microcomputers and novel high-density storage devices will affect the future of toxicology information systems as will impending developments in toxicology itself related to biotechnology, analytical methodology, and alternatives to whole animal testing.

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Section: Early Historymentioning

confidence: 99%

Toxicology information systems: a historical perspective

Kissman¹,

Wexler²

1985

J. Chem. Inf. Comput. Sci.

Self Cite

View full text Add to dashboard Cite

show abstract

“…This clustering or distribution, of course, varies with respect to the number of compounds tested in each bioassay. The Gene-Tox data base will be available online through the NIH/EPA Chemical Information System (7), Toxicology Data Bank (8,9), and Registry of Toxic Effects of Chemical Substances (10).…”

Section: Us Epa Gene-tox Program Agent Registry Filementioning

confidence: 99%

“…The Toxicology Data Bank (TDB) (8,9,13,14) is a factual data base composed of over 4150 comprehensive chemical records. These records contain up to 60 different data elements which are grouped into eight categories.…”

Section: Toxicology Data Bankmentioning

confidence: 99%