The Toxicity and Antibacterial Properties of Calamus ornatus Bl. Rattan Fruit

Salusu, Heriad Daud; Obeth, Ernita; Zarta, Abdul Rasyid; Nurmarini, Eva; Nurkaya, Hamka; Kusuma, Irawan Wijaya; Arung, Enos Tangke

doi:10.22146/agritech.46416

Cited by 3 publications

(3 citation statements)

References 11 publications

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“…Rotan tidak hanya menghasilkan batang, tetapi juga menghasilkan buah yang beberapa di antaranya dapat dikonsumsi. Secara empiris, orang telah memanfaatkan buah rotan untuk menyembuhkan sariawan dan mengobati sakit perut (Salusu et al, 2019). Penelitian yang dilakukan Agen (2016) menemukan hasil bahwa rotan manau (Calamus manan Miq.)…”

Section: Pendahuluanunclassified

Aktivitas Antimikroba Ekstrak Biji Rotan Manau (Calamus manan Miq.) Terhadap Salmonella typhi dan Candida albicans

Mahdiyah,

Maulina,

Hakim

et al. 2024

Al-Kauniyah J. Biol.

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AbstrakDemam tifoid adalah penyakit demam akut yang disebabkan oleh infeksi bakteri Salmonella typhi. Kandidiasis oral merupakan infeksi yang disebabkan oleh fungi Candida albicans yang banyak terdapat pada mukosa rongga mulut. Tujuan dari penelitian yaitu mengidentifikasi aktivitas antimikroba ekstrak biji rotan manau (Calamus manan Miq.) terhadap S. typhi dan C. albicans. Metode ekstraksi yang digunakan adalah metode maserasi dengan pelarut etanol 96%. Skrining antimikroba ekstrak biji rotan manau menggunakan metode well-diffusion. Identifikasi aktivitas antimikroba ekstrak biji rotan manau terhadap S. typhi dan C. albicans untuk melihat Minimum Inhibitory Concentration (MIC) menggunakan metode broth dilution, sedangkan untuk melihat Minimum Bactericidal Concentration (MBC) terhadap S. typhi dan Minimum Fungisidal Concentration (MFC) terhadap C. albicans menggunakan metode solid dilution. Hasil skrining antimikroba didapatkan zona hambat pada ekstrak biji rotan manau terhadap S. typhi sebesar 21,39 mm dan terhadap C. albicans sebesar 16,14 mm. Nilai MIC ekstrak biji rotan manau pada konsentrasi 50% terhadap S. typhi dan C. albicans, sedangkan untuk MBC terhadap S. typhi maupun MFC terhadap C. albicans dari ekstrak biji rotan manau tidak ditemukan karena pada media padat masih ditemukannya pertumbuhan mikroba. Hasil penelitian ini diharapkan dapat menjadi acuan untuk penelitian lanjutan sebagai temuan awal senyawa potensi antimikroba dari ekstrak biji rotan manau terhadap bakteri dan fungi.AbstractTyphoid fever is an acute febrile illness caused by infection with the bacterium Salmonella typhi. Oral candidiasis is an infection caused by the fungus Candida albicans which is abundant in the oral mucosa. The purpose of this study was to identify the antimicrobial activity of rattan manau seed extract (Calamus manan Miq.) against the bacteria Salmonella typhi and the fungus C. albicans. The extraction method used is the maceration method. Antimicrobial screening of rattan manau seed extract using the well-diffusion method. Identification of antimicrobial activity of rattan manau seed extract against S. typhi bacteria and C. albicans fungi to see Minimum Inhibitory Concentration (MIC) using the broth dilution method, while to see Minimum Bactericidal Concentration (MBC) against S. typhi bacteria and Minimum Fungicidal Concentration (MFC) against the fungus C. albicans using the solid dilution method. The results of antimicrobial screening showed that the inhibition zone in the extract of rattan manau against S. typhi was 21.39 mm and against C. albicans was 16.14 mm. The MIC value of rattan manau seed extract was obtained at a concentration of 50% against S. typhi bacteria and C. albicans fungi, while for MBC against S. typhi and MFC against C. albicans from rattan manau seed extract not found because in solid media microbial growth is still found. The results of this study are expected to be a reference for further research as initial findings of antimicrobial potential compounds from the extract of manau rattan seeds against bacteria and fungi.

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Section: Pendahuluanunclassified

Aktivitas Antimikroba Ekstrak Biji Rotan Manau (Calamus manan Miq.) Terhadap Salmonella typhi dan Candida albicans

Mahdiyah,

Maulina,

Hakim

et al. 2024

Al-Kauniyah J. Biol.

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“…Masyarakat di Kalimantan Timur memanfaatkan buah Calamus sp. sebagai obat sakit perut dan sakit gigi (Salusu et al, 2019). Sementara itu, masyarakat tradisional di Taman Nasional Bukit Dua Belas, Sumatra memanfaatkan buah Calamus sp.…”

Section: Buahunclassified

Pakkat (Calamus sp.): Pangan Lokal Masyarakat di Kota Padangsidimpuan

Anggraeni,

Yuniati,

Silalahi

2023

Diversifikasi Pangan Lokal Untuk Ketahanan Pangan: Perspektif Ekonomi, Sosial, dan Budaya

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“…Lethal concentration is the optimum concentration that can kill 50% of organisms in treatment, in this case, shrimp larvae from Artemia salina. The level of toxicity of Schiff base compounds based on the LC50 value can be seen in table I [22].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Toxicity Test of Schiff Base Compound from 4-Formylpyridine and p¬-Anisidine Using Stirrer Method with Water Solvent

Alfin

2021

ICGT

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Abstract- Schiff base is a compound that is produced when primary amine and aldehydes or ketones reacted under certain situations. Schiff base compounds have the characteristic of a C=N (imine) functional group. The Schiff base compound was synthesized from 4-formylpyridine and p-anisidine using a stirrer method with water as the solvent and a 15-minute synthesis time. FTIR spectrophotometer and GC-MS are being used to identify the product of Schiff base compound. The BSLT (Brine Shrimp Lethality Test) method has been used to test the toxicity and LC50 values are used as parameters for the toxic levels of Schiff base compound. The results showed the synthesis product have a yield 99.86%. The product of the synthesis of Schiff base compounds has a physical characteristics such as: greenish-gray solid with a melting point of 91-93.5 oC. The results of characterization using FTIR showed a typical absorption of the C=N group with the target compound at a wavenumber of 1620 cm-1. The results of the GC-MS characterization showed one signal with a retention time of 36.5 minutes and a 100% area. The molecular ion of the m/z was 212, which also corresponded to the molecular weight of the compound 4-methoxy-N-(pyridine-4-ylmethylene)aniline. The results of the toxicity test of Schiff's base compound using the BSLT (Bhrine Shrimp Lethality Test) method showed the presence of toxic properties that have potential as anti-cancer with an LC50 value of 18.66 ppm.

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The Toxicity and Antibacterial Properties of Calamus ornatus Bl. Rattan Fruit

Cited by 3 publications

References 11 publications

Aktivitas Antimikroba Ekstrak Biji Rotan Manau (Calamus manan Miq.) Terhadap Salmonella typhi dan Candida albicans

Aktivitas Antimikroba Ekstrak Biji Rotan Manau (Calamus manan Miq.) Terhadap Salmonella typhi dan Candida albicans

Pakkat (Calamus sp.): Pangan Lokal Masyarakat di Kota Padangsidimpuan

Synthesis and Toxicity Test of Schiff Base Compound from 4-Formylpyridine and p¬-Anisidine Using Stirrer Method with Water Solvent

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