The Topographical Projection of Fibres from the Anterolateral Quadrant of the Spinal Cord to the Subdiencephalic Brain Stem in Man

Bowsher, David

doi:10.1159/000131119

Cited by 76 publications

(12 citation statements)

References 10 publications

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“…The morphology of the vestibular com plex of Galago conforms to the general pattern as seen in opossum [31,61], cat [12], rabbit [69], rat [39], pig [8], Tarsius [64], monkey [15,38,40,45], and man [7,54], A striking feature of the Galago ves tibular complex, however, is its large size relative to the total size of the brain stem [present study, 24, 27], A similar differen tial was also reported by Tilney [64] who believed that this characteristic in Tarsius was related to the hopping locomotor style of this primate. A similar suggestion could be made for Galago since this primate also has a well-developed saltatory locomotor style [44],…”

Section: The Galago Vestibular Nuclei and Associated Subgroupssupporting

confidence: 67%

The Vestibular Complex in a Prosimian Primate <i>(Galago senegalensis): </i>Morphology and Spinovestibular Connections (Part 2 of 2)

Rubertone

Haines

1982

Brain Behav Evol

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The morphology of, and distribution of spinal afferents to, the vestibular complex of a prosimian primate (lesser bushbaby, Galago senegalensis) were studied using cytoarchitectural, myeloarchitectural and selective silver impregnation methods. The vestibular complex of Galago consists of superior (SVN), lateral (LVN), medial (MVN) and spinal (SpVN) nuclei, each nucleus having cell populations of characteristic size, shape and distribution within its borders. There is morphological and experimental evidence for the existence of subgroups f, 1, x, y and z and a hitherto undescribed subgroup located in dorsomedial portions of the rostral two-thirds of the MVN. Following partial or complete hemisections at cord levels C₁-L₆ brain stem sections were impregnated according to the method of Fink and Heimer. Preterminal debris is concentrated mainly in subgroups x and z, relatively sparse in adjacent SpVN and moderate to sparse in LVN and MVN following hemisections at upper and mid-cervical levels. Axonal debris is noticeably absent from the MVN after lesions below the C₈ spinal level; this indicates that the MVN receives spinal input from cervical levels only. Following lesions at C₈ and progressively lower spinal levels, degeneration was found primarily in subgroups x and z and in LVN and SpVN although in lesser amounts; as lesions were placed at progressively lower levels there was a proportionate decrease in the amount of axonal debris found in these respective nuclei. No degeneration was found in SVN following lesions at any spinal level.

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Section: The Galago Vestibular Nuclei and Associated Subgroupssupporting

confidence: 67%

The Vestibular Complex in a Prosimian Primate <i>(Galago senegalensis): </i>Morphology and Spinovestibular Connections (Part 2 of 2)

Rubertone

Haines

1982

Brain Behav Evol

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“…The investigation reported here sought to compare the differences in somatosensory perception thresholds in man consequent upon lesions in the fibres ascending from the anterolateral funiculus of the spinal cord at different levels of the subcortical neuraxis, and to complement and partially explain data presented earlier [17,18,19]. …”

Section: Introductionmentioning

confidence: 99%

Representation of Somatosensory Modalities in Pathways Ascending from the Spinal Anterolateral Funiculus to the Thalamus Demonstrated by Lesions in Man

Bowsher¹

2005

Eur Neurol

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Patients with cordotomies (16), and brainstem (17) or thalamic (30) infarcts, all except cordotomies verified by magnetic resonance imaging (MRI), have been subjected to quantitative sensory perception threshold testing (QST) for touch (von Frey), mechanical pain, sharpness, innocuous warmth and cold, and heat pain in the maximally affected body area and its unaffected contralateral mirror image region. Some patients were tested twice at widely spaced time intervals; no qualitative differences were found. Results show that all modalities are dissociable from one another by lesions at all levels tested, so that there must be separable representation for each of the six modalities tested. In the lower (crossed symptoms and signs), but not the upper (uncrossed symptoms), deficits for all modalities (except for touch) were more marked than at higher levels. At the level of the thalamus, deficits for innocuous and noxious thermal modalities but not for mechanical pain were recorded in the case of lesions of the principal somatosensory relay nucleus (VPL/Vc), while more medial thalamic lesions resulted in deficits for mechanical pain but not for heat pain or innocuous thermal modalities; there is a marked deficit for sharpness caused by lesions at both thalamic sites.

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“…Unit responding by one spike only to stimulation of anterior contralateral limb; two spikes for all the others (= negative preference ac). (Anderson & Berry, 1959), monkey (Mehler, Feferman & Nauta, 1960) and man (Bowsher, 1962). In our own experimental anatomical material in the cat, we have seen bilateral preterminal degeneration in NPC following anterolateral cordotomy, and also following small stereotaxically placed lesions in the caudalmost bulbar RF and in the GC (D. Bowsher, unpublished observations;Bowsher, 1967); both of these latter have been shown by Rossi & Brodal (1957) to receive substantial numbers of spinoreticular terminals.…”

Section: Resultsmentioning

confidence: 84%

Place and modality analysis in nucleus of posterior commissure

Bowsher¹,

Petit²

1970

The Journal of Physiology

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The Topographical Projection of Fibres from the Anterolateral Quadrant of the Spinal Cord to the Subdiencephalic Brain Stem in Man

Cited by 76 publications

References 10 publications

The Vestibular Complex in a Prosimian Primate <i>(Galago senegalensis): </i>Morphology and Spinovestibular Connections (Part 2 of 2)

The Vestibular Complex in a Prosimian Primate <i>(Galago senegalensis): </i>Morphology and Spinovestibular Connections (Part 2 of 2)

Representation of Somatosensory Modalities in Pathways Ascending from the Spinal Anterolateral Funiculus to the Thalamus Demonstrated by Lesions in Man

Place and modality analysis in nucleus of posterior commissure

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