The Topcon SP 1000 and Image-NET Systems

Vecchi, Marco; Braccio, Laura; Orsoni, Jelka G.

doi:10.1097/00003226-199605000-00008

Cited by 21 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This could be because of the fact that the Topcon SP-2000P and z-ring CS4 are both upgraded versions of the SP-1000P and CS3. Other studies using one endothelial image that was read on two occasions independently by two examiners reported that the SP-1000P results show poor test-retest reliability [34,38]. Also, poor agreement between SP-1000P and CS3 to determine ECD is thought to be due to poor image quality [28].…”

Section: Discussionmentioning

confidence: 99%

Assessment of central corneal thickness and corneal endothelial morphology using ultrasound pachymetry, non-contact specular microscopy, and Confoscan 4 confocal microscopy

et al. 2013

View full text Add to dashboard Cite

BackgroundThe aim was to compare the repeatability, reproducibility and inherent precision of ultrasound pachymetry (USP), noncontact specular microscopy (SP-2000P) and the Confoscan 4 confocal microscope (z-ring CS4) in measuring endothelial cell density (ECD), coefficient of variation of cell size (CV), and central corneal thickness (CCT) in normal eyes.MethodsIn this prospective study, one eye was selected from each of 30 subjects for the measurements of ECD, CV and CCT, which were taken by two observers. Results were analyzed statistically by repeated-measures analysis of variance (ANOVA) for intra-observer repeatability, inter-observer reproducibility, unpaired t-test, paired t-test, and Bland–Altman analyses to determine limits of agreement (LOA) between the three instruments.ResultsMean ECD, measured by SP-2000P and z-ring CS4, were 3115.50 ± 279.70 cells/mm2 and 3167.50 ± 264.75 cells/mm2, respectively (observer 1), and 3192.63 ± 249.42 cells/mm2 (z-ring, observer 2). Mean CV measurements were 27.12 ± 2.51 and 27.10 ± 2.41 (SP-2000P and z-ring CS4, respectively; observer 1), and 27.17 ± 2.25 (z-ring, observer 2). Mean CCT values were 555.11 ± 35.83 μm (USP), 535.82 ± 41.10 μm (SP-2000P) and 552.57 ± 36.83 μm (z-ring CS4), and 554.97 ± 36.34 μm (z-ring CS4, observer 2). However, pairwise tests in all cases there was good repeatability and reproducibility as shown by inter-observer and intra-observer analysis of variance for each of the instruments.ConclusionsThe SP-2000P and the z-ring CS4 can be used interchangeably to measure ECD and CV. For CCT, the sample size was too small to test for differences of the CCT measurements between the three instruments.

show abstract

Section: Discussionmentioning

confidence: 99%

Assessment of central corneal thickness and corneal endothelial morphology using ultrasound pachymetry, non-contact specular microscopy, and Confoscan 4 confocal microscopy

et al. 2013

View full text Add to dashboard Cite

show abstract

Prospective, Randomized Clinical and Endothelial Evaluation of 2 Storage Times for Corneal Donor Tissue in Organ Culture at 31°C

Thuret¹,

Chiquet

Bernal

et al. 2003

Arch Ophthalmol

View full text Add to dashboard Cite

To compare the endothelial and clinical outcome of penetrating keratoplasty with corneas stored in organ culture for up to 12 days (5-12 days; group 1) or more than 21 days (21-24 days; group 2). Methods: We conducted a controlled double-masked trial. Storage durations were randomly assigned to the paired corneas, and endothelial cell density (ECD) was measured at the start and end of organ culture. Patients with a low rejection risk and preoperative ECD within the reference range were randomly assigned to 1 of the 2 groups and underwent an 8.25-mm penetrating keratoplasty (n=25 pairs). Follow-up at day 5 and months 1, 6, and 12 included central ECD, morphometry, graft transparency, visual acuity, pachymetry, and complications. The main outcome measure was the central ECD at month 12. Results: At the end of organ culture, ECD of the group 1 corneas was higher by 273 cells/mm 2 (95% confidence interval [CI], 178-368; PϽ.001). One year after penetrating keratoplasty, the group 1 ECD was still comparably higher by 227 cells/mm 2 (95% CI, 43-411; P=.02). Graft transparency, pachymetry, and complication rate did not differ at any time. In group 1, visual acuity was better at month 1. Conclusions: Shorter organ culture allows delivery of corneas with higher ECD. Recipients with ECD within the reference range and low rejection risk retain this initial benefit 1 year postoperatively. The higher endothelial cell capital may prevent or delay late endothelial failure, the leading cause of graft failure in these recipients. We therefore prefer short-term storage for such recipients.

show abstract

Comparison of semi-automated center-dot and fully automated endothelial cell analyses from specular microscopy images

Maruoka¹,

Nakakura²,

Matsuo³

et al. 2017

Int Ophthalmol

View full text Add to dashboard Cite

show abstract

The Topcon SP 1000 and Image-NET Systems

Cited by 21 publications

References 0 publications

Assessment of central corneal thickness and corneal endothelial morphology using ultrasound pachymetry, non-contact specular microscopy, and Confoscan 4 confocal microscopy

Assessment of central corneal thickness and corneal endothelial morphology using ultrasound pachymetry, non-contact specular microscopy, and Confoscan 4 confocal microscopy

Prospective, Randomized Clinical and Endothelial Evaluation of 2 Storage Times for Corneal Donor Tissue in Organ Culture at 31°C

Comparison of semi-automated center-dot and fully automated endothelial cell analyses from specular microscopy images

Contact Info

Product

Resources

About