“…1 Although the ISI has not been validated in OSA samples, it was utilized in several hundred studies and cited 3400 times from 2001 to 2022 in diverse study populations. [2][3][4] Its popularity is reflected by ease of administration and ability to measure both nocturnal insomnia (questions 1-3) and resultant daytime impairment (questions 4-7). However, given shared symptoms between OSA and insomnia resulting in poor sleep quality, the ISI can be falsely elevated when patients experience daytime impairment due to OSA without significant nocturnal insomnia.…”