The three-dimensional structural characterization of hexachlorocyclopentenyl-dibromocyclooctane (HCDBCO)

Riddell, Nicole; Arsenault, Gilles; Lough, Alan J.; McAlees, Alan J.; McCrindle, Robert; Meissner, Joseph; Robertson, Valerie

doi:10.1016/j.chemosphere.2008.06.047

Cited by 10 publications

(7 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A previous study showed that about 1~3% of DBHCTD was degraded by debromination reaction when injector port was maintained at 250 °C27. In the current study, degradation was observed (about 6%) when injector temperature increased to 280 °C.…”

Section: Resultssupporting

confidence: 51%

Atmospheric Pressure Chemical Ionization Gas Chromatography Mass Spectrometry for the Analysis of Selected Emerging Brominated Flame Retardants in Foods

Niu

Zhang

et al. 2017

Sci Rep

View full text Add to dashboard Cite

Emerging brominated flame retardants (eBFRs) other than polybrominated diphenyl ethers (PBDEs), polybrominated biphenyls (PBBs) and their derivatives in foods have been in focus in recent years due to their increasing production volumes, indefinite information on toxicities and the lack of data on occurrence in environments, foods as well as humans. In this study, gas chromatography was coupled to an atmospheric pressure chemical ionization-tandem mass spectrometry (APGC-MS/MS) for the analysis of six eBFRs in pork, chicken, egg, milk and fish. A short section of unpacked capillary column coupled to the end of the analytical column was applied to improve the chromatographic behaviors of high boiling point compounds. The method was comprehensively validated with method limit of quantification (mLOQ) lower than 8 pg/g wet weight (w.w.). Samples from Chinese Total Diet study were quantified following the validated APGC-MS/MS method. 2,3,4,5-pentabromo-6-ethylbenzene (PBEB), hexabromobenzene (HBB), pentabromotoluene (PBT) and 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE) were most frequently detected in samples. The highest concentration was found in fish with 351.9 pg/g w.w. of PBT. This is the first report on the presence of PBT in food samples with non-ignorable concentrations and detection rate.

show abstract

Section: Resultssupporting

confidence: 51%

Atmospheric Pressure Chemical Ionization Gas Chromatography Mass Spectrometry for the Analysis of Selected Emerging Brominated Flame Retardants in Foods

Niu

Zhang

et al. 2017

Sci Rep

View full text Add to dashboard Cite

show abstract

“…It should be noted that DBHCTD has been detected in field and laboratory blanks (Zhu et al, 2008), making it a challenge to achieve low pg/g detection limits. Riddell et al (2008) Zhu et al (2008) identified DBHCTD in residential indoor dust at a mean concentration of 1 600 ng/g dust (LOD 0.12 ng/g) and a maximum concentration of 93 000 ng/g dust. In residential indoor air the mean concentration was 240 pg/m 3 (LOD, 5 pg/m 3 ) and the maximum concentration, 3 000 pg/m 3 .…”

Section: Methods Of Analysismentioning

confidence: 99%

Section: Methods Of Analysismentioning

confidence: 99%

Scientific Opinion on Emerging and Novel Brominated Flame Retardants (BFRs) in Food

2012

EFS2

View full text Add to dashboard Cite

EFSA was asked to deliver a scientific opinion on brominated flame retardants (BFRs) other than PBDEs, PBBs, HBCDDs, TBBPA and brominated phenols and their derivatives. The BFRs that are the subject of the current opinion, were classified in groups termed "emerging" and "novel" BFRs. Information on 17 emerging and 10 novel BFRs was collected. The information varied widely for these BFRs. There is a lack of experimental data on physico-chemical characteristics, stability/reactivity and current use and production volume of all the emerging and novel BFRs. Due to the very limited information on occurrence, exposure and toxicity, the CONTAM Panel could not perform a risk characterisation for any of the BFRs considered. Instead, an attempt was made to identify those BFRs that could be a potential health concern and should be considered first for future investigations. For this purpose the Panel first evaluated the available experimental data on occurrence in food, behaviour in the environment and toxicity. Secondly, a modelling exercise was performed focussing on the potential of the emerging and novel BFRs for persistence in the environment and for their possible bioaccumulation potential. There is convincing evidence that tris(2,3-dibromopropyl) phosphate (TDBPP) and dibromoneopentyl glycol (DBNPG) are genotoxic and carcinogenic, warranting further surveillance of their occurrence in the environment and in food. Based on the limited experimental data on environmental behaviour, 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE) and hexabromobenzene (HBB) were identified as compounds that could raise a concern for bioaccumulation. For the modelling exercise, the CONTAM Panel selected two environmental characteristics, overall persistence and potential for bioaccumulation, as being most relevant to provide insight into the possibility that emerging or novel BFRs The less well known and less studied BFRs, subject of the current opinion, were grouped into two classes, referred to herein as "emerging" and "novel" BFRs. Emerging BFRs are defined as chemicals which are applied as flame retardants and that have been identified in any environmental compartment, in wildlife, in food or in humans. It should be noted that the definition for the emerging BFRs, used in this opinion, does not imply that there is evidence for an increasing trend in the concentration of these BFRs in the environment, in food or in human samples. Novel BFRs are defined as chemicals applied as flame retardants, with confirmed presence in materials and/or goods in concentrations above 0.1 %, but not identified in environmental samples, wildlife, food or humans. In total, information on 27 BFRs, of which 17 were identified as "emerging" and 10 as "novel", was collected by the CONTAM Panel, and it was noted that the available information varied widely for the various individual BFRs.In general, there is a lack of experimental data on physico-chemical characteristics and stability/reactivity for all the emerging and novel BFRs. This sometimes hampered ...

show abstract

“…HCDBCO is unusual as it contains both chlorine and bromine atoms. According to Riddell et al [133] it was first described as a BFR agent in a US patent in 1975. HCDBCO exists as a pair of enantiomers.…”

Section: Introductionmentioning

confidence: 99%

Emerging Brominated Flame Retardants in the Environment

Wit

Kierkegaard

Ricklund

et al. 2010

The Handbook of Environmental Chemistry

View full text Add to dashboard Cite

A number of new brominated flame retardants (BFRs) are being found in the environment but the amount of data is still very small. The best studied emerging BFRs are 1,2-bis(2,4,6-tribromophenoxy)ethane and decabromodiphenyl ethane, with some data for hexabromobenzene, pentabromoethylbenzene, pentabromotoluene, tetrabromobisphenol A derivatives, bis(2-ethylhexyl) tetrabromophthalate, 2-ethylhexyltetrabromobenzoate, 1,2-dibromo-4-(1,2-dibromoethyl) cyclohexane, and 2,4,6-tribromophenol. Very little data are available for 2,4,6-tribromophenyl allyl ether, 2,3-dibromopropyl-2,4,6-tribromophenyl ether, hexachlorocyclopentadienyldibromocyclooctane, tris(2,3-dibromopropyl) isocyanurate, tetrabromophthalic anhydride, 1,2,5,6-tetrabromocyclooctane, and octabromo-1,3,3-trimethyl-1-phenylindane. Indoor air concentrations are generally higher than outdoor air concentrations, indicating emissions from flame-retarded products. Their presence in indoor air and dust indicates possible human exposure from this pathway, but there are little human data available to determine this. The presence of several of these BFRs in fish, birds, and mammals indicates that they are bioavailable and can be absorbed and bioaccumulated. Their presence in outdoor air and in the Arctic indicates that several are capable of long range atmospheric transport. More data on these new BFRs are needed in order to determine if they pose unacceptable risks to the environment and to human health.

show abstract

The three-dimensional structural characterization of hexachlorocyclopentenyl-dibromocyclooctane (HCDBCO)

Cited by 10 publications

References 16 publications

Atmospheric Pressure Chemical Ionization Gas Chromatography Mass Spectrometry for the Analysis of Selected Emerging Brominated Flame Retardants in Foods

Atmospheric Pressure Chemical Ionization Gas Chromatography Mass Spectrometry for the Analysis of Selected Emerging Brominated Flame Retardants in Foods

Scientific Opinion on Emerging and Novel Brominated Flame Retardants (BFRs) in Food

Emerging Brominated Flame Retardants in the Environment

Contact Info

Product

Resources

About