The thoracolumbar spine in Marfan syndrome.

Sponseller, Paul D.; Hobbs, William R.; Riley, Lee H.; Pyeritz, Reed E.

doi:10.2106/00004623-199506000-00007

Cited by 189 publications

(124 citation statements)

References 17 publications

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“…They stated that the back in MFS patients was globally in flexion (with an hyperkyphosis over 50°) in about half of the cases, and that only 8% had a hypokyphosis (a thoracic kyphosis of less than 20°), regardless of the presence of a scoliosis. This gap between our result and the conclusions of Sponseller et al [2] may come from the methodology used. In the work of Sponseller et al [2], the sole lateral view of the spine was considered in order to determine the sagittal balance of the spine.…”

Section: Discussioncontrasting

confidence: 99%

Sagittal balance in scoliosis associated with Marfan syndrome: A stereoradiographic three-dimensional analysis

Glard

Pomero

Collignon

et al. 2008

Journal of Children's Orthopaedics

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Purpose Marfan syndrome (MFS) is a genetic disease often marked by the presence of scoliosis. There is no three-dimensional analysis of the deformity in the literature. Our aim was to determine what kind of sagittal balance defines scoliosis associated with MFS, namely a flexion deformity, as it is in scoliosis associated with Chiari I or an extension deformity, as in adolescent idiopathic scoliosis (AIS). To address this issue, we compared the presence or absence of a thoracic scoliosis with the presence or absence of a segment in extension in the thoracic spine. Methods In our series, 30 patients diagnosed with Marfan syndrome were prospectively included. In each patient, personalized three-dimensional reconstruction from T1 to L5 of the spine was made using stereoradiography. The patients were first separated based on the presence or absence of thoracic scoliosis, in order to compare this with the presence or absence of a segment in extension in the thoracic spine. They were then classified into two groups based on the presence or absence of the segment in extension (meaning containing negative values of intervertebral sagittal rotation) in the thoracic spine.Results Among scoliotic patients with a thoracic scoliosis (17 cases), there were 13 (76.5% cases) with a segment in extension in the thoracic spine and 4 with no segment in extension.Conclusions Our results showed that scoliosis associated with MFS is somehow original, demonstrating a sagittal balance in extension (as AIS) in about 80% of thoracic curves, but without this characteristic feature in about 20%.

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Section: Discussioncontrasting

confidence: 99%

Sagittal balance in scoliosis associated with Marfan syndrome: A stereoradiographic three-dimensional analysis

Glard

Pomero

Collignon

et al. 2008

Journal of Children's Orthopaedics

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“…16,17 Close monitoring by using the forward-bending test at yearly intervals and management by an orthopedist is preferred because surgical stabilization of the spine may be required. 18 FROM THE AMERICAN ACADEMY OF PEDIATRICS however, it is not unique to this condition and is seen in a number of infectious, inflammatory, metabolic, genetic, neoplastic, and traumatic conditions.…”

Section: Skeletalmentioning

confidence: 99%

Health Supervision for Children With Marfan Syndrome

Tinkle¹,

Saal²,

Saul³

et al. 2013

Pediatrics

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“…To date, only three series have been published [2][3][4]. It has been shown that the natural history of the scoliosis associated with MFS is unique and does not resemble that in AIS; it is often more severe [2] in MFS patients, and the King's guidelines used to determine the extent of the arthrodesis in AIS [16,17] does not fit the scoliosis associated with MFS [5][6][7]. A subset of patients with both juvenile and adolescent ''idiopathic'' scoliosis may have an underlying condition that may cause the scoliosis.…”

Section: Discussionmentioning

confidence: 99%

“…Cases of ''non-idiopathic'' scoliosis are deemed ''atypical''. Nevertheless, none of the previously published series investigating MFS scoliosis [2][3][4] focused on the typical versus atypical curve patterns in such patients. The aim of our work was to assess how atypical the scoliosis associated with MFS was, when compared with that of AIS.…”

Section: Discussionmentioning

confidence: 99%